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宫颈环形电切术治疗宫颈上皮内瘤变与随后妊娠流产风险研究 被引量:5

Study on loop electrosurical excision procedure in treatment of cervical intraepithelial neoplasia and the risk of subsequent pregnancy abortion
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摘要 目的评估宫颈环形电切术(LEEP)后妊娠的流产风险,并评估其与LEEP至妊娠时间间隔之间的相关性。方法选取2007年1月-2014年12月行LEEP后妊娠的患者为实验组,选取同期因巴氏涂片见不明意义的非典型鳞状细胞(组织学评估为宫颈低度病变,无需宫颈切除或消融术)行阴道镜检查的患者为对照组。通过查找病历和电话随访收集患者的妊娠时间、妊娠周数、妊娠结局和终止妊娠方式等资料。结果在LEEP至妊娠时间间隔<12个月的患者中,流产率显著升高,而在LEEP至妊娠时间间隔≥12个月的患者中,流产率与对照组比较差异无统计学意义(P>0.05)。结论这些发现可能帮助提供LEEP术后妊娠的最佳时机,以减少流产的风险。 Objective To evaluate the risk of pregnancy abortion after loop electrosurical excision procedure (LEEP) and the correlation with time interval between LEEP and subsequent pregnancy. Methods The pregnant women 'after LEEP were selected as experimental group from January 2007 to December 2014, while the patients undergoing colposcopy because of atypical squamous cell carcinoma of undetermined significance (ASCUS) (low-grade cervical lesion, cervicectomy and cervical 'ablation are unnecessary) diagnosed by Papanicolaou smears dur- ing.the same period were selected as control group. The pregnancy time, pregnancy weeks, pregnancy outcome, and methods of terminating pregnancy were collected by looking up medical records and telephone follow-up. Results Among the patients with time interval between LEEP and subsequent pregnaney〈12 months, the rate of abortion increased significantly; among the patients with time interval between LEEP and subsequent pregnancy≥ 12 months, there was no statistically significant difference in the rate of "abortion between the two groups (P〉 0. 05). Conclusion These findings may provide the best opportunity to get pregnancy and reduce the risk of miscarriage after LEEP.
出处 《中国妇幼保健》 CAS 2016年第18期3715-3717,共3页 Maternal and Child Health Care of China
关键词 宫颈环形电切术 妊娠 宫颈上皮内瘤变 流产 Loop electrosurical excision procedure Pregnancy Cervical intraepithelial neoplasia Abortion
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二级参考文献24

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