摘要
目的:探究清热凉血化瘀法对上肢骨折围术期TNF-α和IL-6的影响。方法:选择2015年03月至2016年03月入我院诊断为上肢骨折手术治疗患者共66例,采用随机数字法将其分为对照组和观察组各33例,对照组采用常规围术期治疗,观察组联合应用清热凉血化瘀法,14 d后对比围术期并发症包括疼痛和肿胀发生率,血清TNF-α和IL-6的水平。结果:观察组的并发症发生率低于对照组,差异有统计学意义(P<0.05)。入院第2 d患者的IL-6和TNF-α水平相比,差异无统计学意义(P>0.05);入院第7 d、术后第2 d和7 d的IL-6和TNF-α水平均下降,且观察组显著低于对照组,差异有统计学意义(P<0.05)。结论:清热凉血化瘀法应用于上肢骨折围术期可减少并发症,与降低血清TNF-α和IL-6水平有关。
Objective： To study the influence of Qingre liangxue huayu method on upper limb fracture of TNF-a and IL-6 levels in perioperative period. Methods： A total of 66 consecutives from March 2015 to March 2016 were divided into control and observation groups by the random number method, and each of 33 cases. The patients in control group received common treatment, and they in ob- servation group were adopted Qingre liangxue huayu method, then to compare the complications rate including pain and swelling, the levels of serum TNF-a and IL-6. Results： The complications rate in observation group was significantly lower than control group （P 〈 0.05 ） . The levels of serum TNF-a and IL-6 after 7days and 14days in the two groups were all lower than before, what＇ s more, they in observation group were significantly lower than control group （P 〈 0. 05 ） . Conclusion： Qingre liangxue huayu method on upper limb fracture could greatly decrease perioperative complications, which may be related to lowering serum TNF-a and IL-6 levels.
出处
《成都中医药大学学报》
2016年第3期67-69,73,共4页
Journal of Chengdu University of Traditional Chinese Medicine
