摘要
目的:评价益肾补脾加减方对慢性肾脏病(CKD)3期脾肾气虚证患者生活质量的影响。方法:60例CKD3期患者随机分为治疗组30例和对照组30例,两组患者均给予常规西医治疗,治疗组在西医治疗基础上采用益肾补脾方加减,观察治疗前后生活质量量表、中医证候积分、血清白蛋白、血红蛋白、肾小球滤过率、血肌酐、血尿素氮的改变。结果:(1)两组患者中医证候总积分的比较:治疗组与基础治疗对照组比较,治疗组更能明显改善中医证候总积分(P<0.01);(2)两组患者生活质量量表各维度积分的比较:治疗组与对照组比较,中医辨证治疗组更能明显改善生活质量(P<0.01);(3)两组患者中医临床症状的比较:中医辨证治疗组对倦怠乏力、气短懒言、腰膝酸软、肢体困重、食少纳差等中医症状的改善明显优于基础治疗对照组(P<0.01);(4)两组患者理化检查指标的比较:中医辨证治疗组对改善患者肾小球滤过率、血肌酐、血尿素氮、血清蛋白、血红蛋白等方面明显优于基础治疗对照组(P<0.01)。结论:益肾补脾加减方可明显改善CKD3期脾肾气虚证患者临床症状和提高患者生命质量,延缓慢性肾脏病病程的进展。
Objective： To evaluate the Effect of Spleen- invigorating and kidney- tonifying decoction on the Quality of life in deficiency of spleen and kidney Patients With Chronic Kidney Disease at the 3 Stage. Methods： 60 cases with CKD 3 stage were randomly divided into control group（ n = 30） and thetreatment group（ n = 40）. The two groups were given conventional western medicine therapy,the experimental group on this basis,dialectics and to Spleen- invigorating and kidney- tonifying treatment. After12 weeks of treatment,the charger of quality of life scale,TCM syndrome integral points,serum albumin,hemoglobin,glomerular filtration rate,serum creatinine,blood urea nitrogen were observed. Results：（ 1） Compared two groups of patients with TCM syndrome total score： TCM treatment group and the control group comparison,TCM treatment group can significantly improve the TCM syndrome total score（ P〈0. 01）.（ 2） Two patients quality of life scale integral comparison： TCM treatment group and control group comparison,TCM treatment group can obviously improve the quality of life（ P〈0. 01）.（ 3） Compared two groups of patients with clinical symptoms of TCM： TCM treatment group of fatigue,shortness of breath,Yaoxisuanruan,heaviness in the body,eat less anorexia and other symptoms of traditional Chinese medicine is better than the basic treatment control group（ P〈0. 01）.（ 4） Patients in the two group comparison of physical and chemical indexes： TCM treatment group to the control group improved in patients with glomerular filtration rate,serum creatinine,blood urea nitrogen,serum protein,hemoglobin and other aspects of treatment is obviously better than the foundation（ P〈0. 01）. Conclusion： Spleen- invigorating and kidney- tonifying decoction on the Quality of life in deficiency of spleen and kidney Patients With Chronic Kidney Disease at the 3 Stage,can obviously improve the clinical symptoms and improve the life quality of patients with stable renal function,and can slowing
出处
《中国中西医结合肾病杂志》
2016年第8期692-695,共4页
Chinese Journal of Integrated Traditional and Western Nephrology
基金
广西壮族自治区科技攻关计划项目(No.桂科攻12300019)
关键词
益肾补脾
慢性肾脏病
生活质量
脾肾气虚
Spleen-invigorating and kidney-tonifying method
Chronic kidney disease
Quality of life
Deficiency of spleen and kidney
