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甲状腺功能正常孕妇孕早期甲状腺过氧化物酶抗体滴度与产后甲状腺炎发生率相关性研究

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摘要 目的探讨孕甲状腺功能正常孕妇孕早期甲状腺过氧化物酶抗体(TPOAb)滴度与产后甲状腺炎(PPT)发生率是否存在相关性。方法:根据TPOAb滴度高低不同将孕早期TPOAb阳性但甲状腺功能正常的100名孕妇组分为4组,其中5.94 ulU/mlTPOAb〈200 uiu/m1组25名、200≤TPOAb 500 uIU/ml组28名、500≤TPOAb〈1000 uIU/ml组26名,≥i000 uIU/ml组21名,分别统计各组PPT发生率及并进行相关统计学分析。结果:TPOAb滴度不同的四组孕妇PPT发生率分别为12.00%、21.43%、19.23%3 23.81%,统计学结果无显著差异性(x2=1.208,P=O.751)。结论:孕早期甲状腺过氧化物酶抗体阳性但甲功正常的孕妇其抗体滴度与产后甲状腺炎发生率无相关性。 Objective To investigate the early pregnancy thyroid peroxidase antibody(TPOAb) titer and the incidence of postpartum thyroiditis(PPT) whether there is a correlation.Methods:According to titer of TPOAb, 100 cases were divided into 4 groups, 25 cases in 5.94uIU/mlTPOAb〈2OOulU/ml group, 28 cases in 200 ulU/ml 〈TPOAb〈500ulU/ml group, 26 cases in 500ulU/ml TPOAb〈1000uIU/ml group and 21cases in〉 lO00ulU/ml group, Statistics on the incidence PPT in each group and analyze whether there is a correlation.Results:The incidence ofPPT were 12%,21.43%,19.23% and 23.81% respectively in 4 groups patients, and the result have no significant difference (x2=1.208,P=0.751).Conclusion:There was no correlation between titer of TPOAb in early pregnancy with normal thyroid function and PPT.
出处 《世界中医药》 CAS 2016年第B03期1573-1574,共2页 World Chinese Medicine
基金 深圳市福田区级科研课题(FTWS2014034)
关键词 孕早期 甲状腺过氧化物酶抗体 滴度 产后甲状腺炎 相关性 early pregnancy thyroid peroxidase antibody titer postpartum thyroiditis relativity
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