摘要
目的观察研究咽异感症与胃食管反流的关系。方法将2014年2月～2015年2月收治的60例合并胃食管反流病的患者分为两组，每组30例。对照组给予上清片治疗，观察组接受雷贝拉唑＋莫沙必利＋上清片治疗。应用Synectics Digitrapper便携式pH监测仪和Syn—ectics Bilitec2000胆汁监测仪进行食管内24h动态pH和胆汁监测，并对两组患者临床疗效进行统计学分析。结果观察组患者的反流率为33．3％，明显低于对照组的66．7％，差异具有统计学意义（P〈0．05）；观察组患者胃食管反流病、咽异感症治疗总有效率分别为86．7％、93．3％，明显高于对照组的76．7％、73．3％，差异具有统计学意义（P〈0．05）。结论病理性胃食管反流患者可伴有咽异感症，两者具有相关性，给予抑酸治疗后疗效满意，说明胃食管反流病可能是咽异感症的重要病因之一。
Objective To observe the relationship between pharyngeal paraesthesia and gastroesophageal reflux. Methods 60 cases of patients with gastroesophageal reflux disease cured in our hospital from February 2014 to February 2015 were divided into two groups,30 cases in each group.Patients in the control group were given supernatant tablets therapy,patients in the observation group were given Rabeprazole＋Mosapride＋supernatant tablets therapy.Synectics Digitrapper ambulatory pH monitoring and Synectics Bilitec 2000 bile monitoring were used to monitor 24h dynamic pH and bile in the esophagus.Clinical curative effects of the two groups were statistically analyzed： Results Reflux of patients in the observation group was 33.3%, which was significantly lower than that in the control group with 66.7%,the difference was statistically significa0t （P 〈 0.05）.Gastroesophageal reflux disease and pharyngeal paraesthesia total effective rate of the observation group respectively were 86.7%,93.3%,which were significantly higher than those of the control group with 76.7%,73.3%,the differences were statistically significant （P 〈 0.05）. Conclusion The patients with pathologic gastroesophageal reflux disease might be accompanied by pharyngeal paraesthesia.There were correlations between them.It was satisfied with the efficacy of anti-acid therapy,which showed that gastroesophageal reflux disease might be an important cause of pharyngeal paraesthesia.
出处
《中国医药科学》
2016年第15期204-207,共4页
China Medicine And Pharmacy
关键词
胃食管反流
咽异感症
雷贝拉唑
莫沙必利
抑酸治疗
Gastroesophageal reflux
Pharyngeal paraesthesia
Rabeprazole
Mosapride
Anti-acid therapy
