摘要
心力衰竭(HF)是指由心脏结构或功能异常导致心室收缩或舒张能力受损进而引起一系列病理生理变化的临床综合征。HF是大多数心血管疾病的最终归宿,其患病人口、死亡率及医疗支出在世界范围内均占据重要比重。为了更有效地治疗HF、提高患者的生存率,新型HF治疗药物的研究不断深入。新型HF治疗药物包括双效神经激素调节剂、强心剂、血管活性多肽与心肌保护剂。本文简要综述近年治疗HF新型药物的研究进展。
Heart failure（HF） is a clinical syndrome caused by abnormal cardiac structure or function,which lead to impaired ventricular contractility or impaired diastolic function and thus lead to a series of pathological and physiological changes.HF is ultimate destination of most cardiovascular diseases,its prevalence,mortality and health care expenditure have accounted for a significant proportion of the world＇s population.In order to improve the curative effect of HF and the survival rate of patients,new HF therapeutics research has also been in-depth exploration.The new fashioned drugs of HF treatment include double neurohormonal regulator,cardiac stimulant,vasoactive intestinal peptide and myocardial protective agent.This review describes the research progress of new drugs for HF.
出处
《世界临床药物》
CAS
2016年第9期643-648,共6页
World Clinical Drug
