摘要
目的 :探讨肺痹汤与阿奇霉素联合应用治疗特发性肺间质纤维化的临床疗效。方法 :将60例确诊为特发性肺间质纤维化的患者随机分为肺痹汤组、阿奇霉素组及联合用药组,每组各20例。三组均给予常规治疗(低流量吸氧+止咳化痰+抗感染+激素治疗),肺痹汤组加用肺痹汤,阿奇霉素组加用阿奇霉素,联合用药组同时加用肺痹汤与阿奇霉素,均连续用药15 d。结果:治疗后三组患者的临床表现、肺功能均有不同程度的改善,联合用药组症状改善更为明显,肺活量(VC)与动脉氧分压(Pa O2)值提高更显著,联合用药组总有效率高于其他两组,治疗过程中均未发生明显不良反应。结论:肺痹汤与阿奇霉素联合应用在治疗特发性肺间质纤维化方面有较好效果。
Objective：To explore the clinical curative idiopathic pulmonary fibrosis. Methods ：A total of 60 effect of Feibi decoction combined with azithromycin on patients who were diagnosed as idiopathic pulmonary fi- brosis were randomly divided into Feibi decoction group,azithromycin group and combination group,with 20 cases in each group. All the three groups were given conventional treatment（low flow oxygen＋relieving cough and reducing sputum＋anti-infection＋hormone therapy）. On the basis of the conventional treatment,Feibi de- coction was added to the Feibi decoction group,azithromycin was added to the azithromycin group and Feibi decoction and azithromyein were added to the combination group. All the medicines were taken continuously for 15 days. ResultS：After treatment,the clinical manifestations and lung function of all the three groups were improved in different degree. In the combination group,symptoms of the patients were improved more obviously,the vital capacity（VC） and arterial oxygen partial pressure（PaO2） were improved more prominent, and the effective rate was higher than that of the other two groups. There were no obvious adverse reactions in the three groups during the process of treatment. Conclusion：Feibi decoction combined with azithromycin has better effect on the treatment of idiopathic pulmonary fibrosis.
出处
《山东中医杂志》
2016年第8期710-712,共3页
Shandong Journal of Traditional Chinese Medicine
关键词
肺痹汤
阿奇霉素
特发性肺间质纤维化
疗效观察
Feibi decoction
azithromycin
idiopathic pulmonary fibrosis
observation of curative effect
