摘要
目的:观察益气宣肺散内服联合穴位贴敷治疗老年急性支气管炎患者的临床疗效,并重点研究其对患者肺功能、血气分析指标的影响。方法:将2013年3月—2015年7月于本院就诊的老年急性支气管炎患者116例随机分为对照组和观察组各58例,对照组患者给予常规西医治疗,观察组患者在常规治疗的基础上联合给予益气宣肺散内服联合穴位贴敷治疗,两组均连续治疗1周。比较两组临床治疗的有效性,观察临床症状变化,评价其呼吸道中医证候积分并对症状改善时间进行统计,监测机体炎性因子水平,检测肺功能及血气分析指标改善情况,记录不良反应。结果:观察组的临床症状改善明显优于对照组患者,其中医证候积分较对照组明显降低,各临床症状的缓解时间较对照组更短,有效率91.4%较对照组74.1%明显升高,差异性显著(P<0.05);两组患者的机体炎性因子hs-CRP、TNF-α、IL-6水平较治疗前降低明显,以观察组患者的降低幅度更大,差异性显著(P<0.05);两组患者的肺功能及血气分析指标经治疗后均有所改善,观察组患者肺功能相关指标FVC、FEV1、PEF%较对照组患者明显升高,血气分析指标Pa O2显著高于对照组患者,Pa CO2水平则较对照组明显降低,差异性显著(P<0.05)。结论:益气宣肺散内服联合穴位贴敷利于改善老年急性支气管炎患者的临床症状,缩短病程,疗效肯定,其机制与抗炎、改善肺功能与血气分析指标有一定的相关性,凸显出中医内外合治呼吸系统疾病的优势与特色,值得临床深入探究。
Objective： To investigate the clinical efficacy of treating elderly patients with acute bronchitis with Yiqi Xuanfei Powder and point application therapy and the influence of pulmonary function and blood gas analysis index. Methods： A total of116 acute bronchitis elderly patients were randomly divided into a control group with 58 cases and an observation group with 58 cases from March 2013 to July 2015. Patients in the control group were treated with conventional western medicine therapy while patients in the observation group were treated with Yiqi Xuanfei Powder and point application therapy on the basis of conventional western medicine therapy for one week. The paper focused on comparing the effectiveness,observing the change of clinical symptom,evaluating the main respiratory syndromes points,recording the improvement time of the main symptoms,testing the levels of inflammatory factors,monitoring the changes of lung function and the blood gas analysis index and finally recording the adverse reactions. Results： Observation group’ s clinical symptoms were improved significantly better than that of the control group and the symptoms scores were lower than that of the control group and the improvement time of the main symptoms was shorter than that of the control group. The efficiency of patients in the observation group was 91. 4%,which was higher than the control group’ s74. 1%. The difference was significant（ P 〈 0. 05）. The levels of the body’s inflammatory factor,such as hs- CRP,TNF- α and IL- 6 went up after treatment. The degree change of the observation group was bigger than that of the control group and the difference was significant（ P 〈 0. 05）. The pulmonary function and blood gas analysis index of the two groups were improved after treatment. The levels of FVC,FEV1 and PEF% for the patients in the observation group were higher than those of the control group and the level of PaO 2was also higher than that of the control group,but the level of PaC O2 was lower than that of the
出处
《辽宁中医杂志》
CAS
北大核心
2016年第8期1645-1648,共4页
Liaoning Journal of Traditional Chinese Medicine
关键词
老年
急性支气管炎
益气宣肺散
穴位贴敷
肺功能
血气分析
elderly patients
acute bronchitis
Yiqi Xuanfei Powder
point application therapy
pulmonary function
blood gas analysis index
