摘要
目的:检测miRNA-140在胃窦癌患者中的表达水平,并探讨其与胃窦癌临床病理的关系。方法:选取我院47例胃窦癌患者并采用RT-PCR法检测血清中miR-140。结果:miR-140的表达水平与胃窦癌分化程度、临床分期及淋巴结转移相关,差异有统计学意义(P<0.05),而与患者性别、年龄均无相关性(P>0.05)。结论:miR-140在胃窦癌患者中的低表达可能与胃窦癌的发生发展有关。
Objective：The miRNA-140 expression level in patients with gastric antrum cancer was studied.And its relationship with clinical pathology of gastric antrum cancer was explored.Methods：To select 47 patients with gas-tric antrum carcinoma and by RT-PCR method to detect serum miR-140.Results：The expression of miR-140 lev-el and the degree of gastric antrum carcinoma differentiation ,clinical stage ,lymph node metastasis was related （P〈0.05）,while in gender and age,had no correlation （P〉0.05）.Conclusion：The lower expression of miR-140 in patients with gastric antrum cnacer may be related with gastric antrum cancer occurrence and development.
出处
《现代肿瘤医学》
CAS
2016年第19期3077-3078,共2页
Journal of Modern Oncology
基金
陕西省自然科学基金面上项目(编号:2014JM2-3035)
