摘要
目的 探讨硝苯地平治疗子痫前期的效果。方法 选取2013年10月~2015年10月我院接收的74例子痫前期患者,根据入院先后顺序分组,各37例。对照组仅采用硫酸镁注射液,研究组在对照组基础上加用硝苯地平。统计两组临床疗效、舒张压及收缩压水平、血细胞比容、尿蛋白含量变化情况和妊娠结局。结果 研究组治疗总有效率为94.60%、新生儿窒息发生率为2.7%、剖宫产率为10.8%,高于对照组（72.97%、21.6%、40.5%）,差异有统计学意义（P〈0.05）;治疗前两组舒张压及收缩压水平、血细胞比容、尿蛋白含量比较,差异无统计学意义（P〉0.05）,经治疗,研究组各指标均明显优于对照组,差异有统计学意义（P〈0.05）。结论 在常规治疗基础上加用硝苯地平治疗子痫前期效果确切,可有效改善患者血压水平、血细胞比容、尿蛋白含量,改善妊娠结局,提高临床疗效。
Objective To explore the curative effect of Nifedipine for the treatment of preeclampsia.Methods 74 patients with preeelampsia who had received treatment in our hospital between October 2013 and October 2015 were selected and divided into two groups according to the admission order.Control group was treated with magnesium sulfate injection,whereas the study group with Nifedipine and magnesium sulfate injection.The clinical efficacy, diastolic and systolic blood pressure,hematoerit,ehanges of urine protein and pregnancy outcomes in the two groups were statistically analyzed.ResMts The total effective rate （94.60%）,neonatal asphyxia rate （2.7%）,rate of cesarean section （10.8%） in the study group were all higher than those of control group （72.97%, 21.6% and 40.5% respeetively）,and the differences were statistically significant （P〈0.05）.There was no statistically significant difference registered between the two groups in systolic and diastolic blood pressure,hematocrit and proteinuria content before treatment （P〉0.05）.After treatment, however, all these indexes in the study group were shown to be significantly better than those of control group,and the differences were statistically significant （P〈0.05）.Conelusion For the treatment of preeclampsia,Nifedipine combined with conventional treatment is with definite curative effect,which can effectively improve the patients＇ blood pressure, hematocrit,urine protein content,pregnancy outcomes and clinical effects.
出处
《中国当代医药》
2016年第24期87-89,共3页
China Modern Medicine
关键词
硝苯地平
硫酸镁
子痫前期
妊娠
Nifedipine
Magnesium Sulfate
Preeclampsia
Gestation
