摘要
背景与目的:围术期低体温会影响肿瘤患者的预后,静脉输注氨基酸可以通过内源性产热升高体温,充气式升温机是普遍使用的治疗低体温的一种物理方式。本研究探讨静脉输注氨基酸对肿瘤患者术后低体温是否有治疗效果及与升温机相比的疗效。方法:选取57例胃癌患者,ASAⅠ~Ⅱ级,年龄18~60岁,在硬膜外复合全身麻醉下行胃癌根治术,术后中心温度低于36℃。进入苏醒室后随机分为3组(n=19):A组静脉输注氨基酸,速度2 m L·kg^(-1)·h^(-1);B组给予充气式升温机;C组未给予干预措施。1 h内每5 min记录1次直肠体温及热舒适度,之后在2、6和24 h时分别记录口腔温度及热舒适度。患者进入苏醒室时及1 h后分别进行1次血气分析。结果:1 h时,A组和B组之间体温和热舒适度差异无统计学意义(P>0.05),但均显著高于C组(P<0.05);2和6 h时,A组体温和热舒适度明显高于B组和C组(P<0.05),B组和C组之间体温和热舒适度差异无统计学意义(P>0.05);24 h时,3组之间体温和热舒适度差异无统计学意义(P>0.05)。结论:静脉输注氨基酸升温效果优于充气式升温机,是治疗术后低体温更为有效便捷的方法。
Background and purpose： Perioperative hypothermia will affect the prognosis of cancer patients. Amino acid infusion can increase the core temperature by endogenous thermogenesis. And the forced-air warming system has gained high acceptance as a measure for rewarming. This study aimed to find out whether amino acid infusion was effective to treat postoperative hypothermia and how well the treatment effect was when Compared with the forced-air warming system. Methods： Fifty-seven ASA I or ]I patients aged 18-60 years undergoing elective esophageal or gastric cancer operation under epidural-general anesthesia and whose core temperature were below 36 ℃. When admitted to the recovery room were randomly divided into 3 groups （n=19）： Group I received intravenous infusion of mixed amino acid at a rate of 2 mL·g-1·h-1 （A）; GroupⅡ received a forced-air system （B）; group Ⅲ received no therapy （C）. Rectal temperature and thermal comfort were recorded per 5 rain during the first 1 h and oral temperature and thermal comfort were recorded at the 2, 6 and 24 h. ABG was recorded when patients were admitted to the recovery room and at the first hour. Results： At the first hour, the rectal temperature and thermal comfort of groups A and B were higher when compared with group C （P〈0.05）, and there was no difference between groups A and B （P〉0.05）. At the second and sixthhour, the temperature and thermal comfort of group A were higher when compared with group B and C （P〈0.05）, and there was no difference between groups B and C （P〉0.05）. At the 24th hour, there were no statistically significant differences in the temperature and thermal comfort among the three groups （P〉0.05）.Conclusion： The rewarming effect of infusion of mixed amino acid is better than that of the forced-air warming system It is the more effective and convenient method to rewarm the postoperative hypothermia.
出处
《中国癌症杂志》
CAS
CSCD
北大核心
2016年第8期682-686,共5页
China Oncology
关键词
复合氨基酸
充气式升温机
术后低体温
肿瘤转移
Mixed amino acid
Forced-air warming system
Postoperative hypothermia
Tumor metastasis
