摘要
目的:借助FibroScan手段,了解不同中医证型的NALFLD肝脏纤维化病变情况。方法:选取NALFLD患者357例,进行辨证分析后,分为肝郁脾虚、痰湿阻滞证组122例,痰阻血瘀、湿郁化热证组118例,湿郁血瘀,肝阴不足证组117例。三组患者分别进行FibroScan检测,对其中愿意接受肝穿刺的患者进一步进行肝活检。分别比较不同中医证型组别间FibroScan测值差异性、肝活检结果的差异性、FibroScan测值与肝活检结果的符合程度。结果:痰阻血瘀、湿郁化热证和湿郁血瘀、肝阴不足证与肝郁脾虚、痰湿阻滞证的FibroScan测值差异有统计学意义(P<0.01),前两组中度以上肝纤维化增加;而三组证型的肝活检结果差异无统计学意义(P>0.05);FibroScan与肝活检在诊断三组证型患者轻度、中度以上肝纤维化差异无统计学意义(P>0.05)。结论:运用无创肝纤维化检测手段FibroScan具有重要意义。
Objective： To understand the liver fibrosis of NAFLD in different TCM syndrome types by means of FibroScan. Methods： 357 cases of pa- tients with NALFLD were divided into syndrome group of 122 Ganyupixu Tanshizuzhi cases, syndrome group of 118 Tanzuxueyu Shiyuhuare cases, syn- drome group of 117 Shiyuxueyu Ganyinbuzu cases by TCM syndrome differentiation. FibroScan were tested in three groups of patients, and the patients who were willing to accept liver biopsy were further performed liver biopsy. Compare the difference value of FibroScan of TCM groups, the difference of liver biopsy results of TCM groups, the coincidence between value of FibroScan and liver biopsy results. Conclusion： Extremely significant differences exist in the value of FibroScan between the group of Tanzuxueyu Shiyuhure and Shiyuxueyu Ganyinbuzu with the group of Ganyupixu Tanshizuzhi （ P 〈 0. 01 ） ,and the group of Tanzuxueyu Shiyuh^e and Shiyuxueyu Ganyinbuzu show more liver fibrosis. There was no significant difference in liver biopsy results between the three TCM groups （P 〉 0. 05 ）. It is same in the diagnosis of three TCM groups of patients with mild, moderate or above liver fibrosis with FibroScan and liver biopsy （P 〉 0. 05 ）.
出处
《内蒙古中医药》
2016年第9期2-3,共2页
Inner Mongolia Journal of Traditional Chinese Medicine
基金
佛山市科技局立项课题
项目编号:201308065
