摘要
目的:观察综合治疗加高压氧治疗对自发性脑出血患者的临床疗效。方法:脑出血患者1270例分为2组,对照组590例实行开颅去骨瓣减压、钻孔引流、脑室引流等手术及对症、支持等综合治疗措施;研究组680例在对照组的基础上尽早给予高压氧进行治疗。治疗后比较2组临床疗效、死亡率及治疗前、后格拉斯哥昏迷指数(GCS)、Fugl-Meyer运动功能量表(FMA)、改良Barthel指数(MBI)评分。结果:治疗3个月后,研究组总有效率明显高于对照组(P<0.05);研究组死亡率明显低于对照组(P<0.05)。治疗后,2组GCS、FMA及MBI评分均较治疗前明显提高(P<0.05),且研究组更高于对照组(P<0.05)。结论:在综合治疗的基础上采用高压氧对自发性脑出血患者进行尽早治疗可有效的提高治疗效果,降低死亡率,并改善预后。
Objective： To evaluate the clinical efficacy of comprehensive treatment plus hyperbaric oxygen therapy on spontaneous intracerebral hemorrhage patients. Method： 680 cases of spontaneous intracerebral hemorrhage ad mitted in Wuhan Brain Hospital from January 2011 to May 2015 were selected as the study group, and 590 cases from January 2004 to December 2010 served as the control group. Control group was given decomprcssive craniecto- my, drilling drainage, or ventricular drainage and other comprehensive treatments. Study group received hyperbaric oxygen therapy on the basis of comprehensive treatment. Clinical efficacy, mortality, activities of daily living and motor function were evaluated before and after treatment. Result： The total effective rate in the study group was significantly higher than that in the control group （P〈0.05）. The mortality rate in the study group was significant- ly lower than that in the control group （P〈0.01）. The GCS scores, limb motor function scores （Fugl-Meyer motor function score, FMA） and activities of daily living scores （Modified Barthel index, MBI） showed no significant difference between two groups before treatment （P〉0.05）. After treatment, the scores in the two groups were sig- nificantly lower than those before treatment （P〈0.05）, and the scores in the study group were significantly higher than those in the control group （P〈0.01）. Conclusion： On the basis of the comprehensive therapy, the use of hy-perbaric oxygen therapy on patients with spontaneous intracerebral hemorrhage can effectively improve the curative efficacy, reduce mortality and improve prognosis.
出处
《中国康复》
2016年第4期246-248,共3页
Chinese Journal of Rehabilitation
关键词
综合治疗
高压氧
自发性脑出血
comprehensive treatment
hyperbaric oxygen
spontaneous intracerebral hemorrhage
