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前列腺素E1治疗肝硬化应用效果初步观察与评估

Preliminary Observation and Evaluation of the Effect of Prostaglandin E1 in the Treatment of Liver Cirrhosis
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摘要 目的研究前列腺素E1治疗肝硬化的应用效果。方法方便选取该院2014年1月—2015年12月住院接受治疗的70例肝硬化病人。病人分组方法:随机抽签法。70例病人分为常规组和干预组2个组别。常规组给予内科综合治疗;干预组加前列腺素E1治疗。观察指标:1病情控制率;2治疗前和治疗后病人血清HA、LN、CIV、PcⅢ水平的差异。结果 1干预组相比于常规组病情控制率更高,χ2检验差异有统计学意义,P<0.05;2治疗前两组血清HA、LN、CIV、PcⅢ水平相似,t检验差异无统计学意义,P>0.05;治疗后干预组相比于常规组血清HA、LN、CIV、PcⅢ水平改善更显著,t检验差异有统计学意义,P<0.05。结论前列腺素E1治疗肝硬化应用效果确切,可有效延缓肝硬化进展,值得推广。 Objective To study the effect of prostaglandin E1 in the treatment of liver cirrhosis. Methods 83 cases of pa-tients with cirrhosis who were hospitalized in our hospital from January 2014 to December 2015. Patient group method:ran-dom draw.83 patients were divided into two groups: the conventional group and the intervention group. The routine group was given comprehensive treatment in the Department of internal medicine,and the intervention group was treated with prostaglandin E1.Observation index:①The disease control rate;②Before and after treatment,serum levels of HA,LN,CIV,Pc III were different. Results ①In the intervention group compared to conventional group condition control rate higher,the X2 statistic treatment there was a significant difference,P﹤0.05; ②Treatment of two groups of serum HA,LN,civ,PC III levels similar,the t statistic treatment had no significant difference (P〉0.05);after treatment,the intervention group than in the con-ventional group blood Qing ha,LN,civ,PC III levels significantly improved,the t statistic treatment there was a significant difference,P﹤0.05). Conclusion The effect of prostaglandin E1 in the treatment of liver cirrhosis is exact, which can effec-tively delay the progression of liver cirrhosis,and it is worth popularizing.
作者 翟爱荣
出处 《中外医疗》 2016年第18期135-136,共2页 China & Foreign Medical Treatment
关键词 前列腺素E1 肝硬化 应用效果 Prostaglandin El Liver cirrhosis Application effect
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