摘要
结合中医络病、癥瘕、聚散理论,笔者认为慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)的基本病机是微型癥瘕痹阻肺络,该假说与西医的气道重构具有一致性。在传统中医四诊的基础上,本文将现代分子生物学理论与COPD辨证分型相结合,揭示了肺络微型癥瘕的内涵,为COPD的临床辨证和个体化治疗提供新的参考依据,同时也为药物作用机制研究奠定基础。
Combined with the theories of collateral disease,abdominal mass and the theory of accumulating and dissipating in Chinese medicine,we consider that micro-zhengjia in feiluo is the basic pathogenesis in COPD,and the hypothesis has coherence with airway remodeling in Western medicine. On the basis of four diagnostic methods of TCM,we combine the theory of modern molecular biology with COPD syndrome differentiation to reveal the connotation of micro-zhengjia in feiluo. It not only provides the reference basis of syndrome differentiation and individual treatment of COPD,but also lays a foundation of study of mechanism of medicine.
出处
《环球中医药》
CAS
2016年第8期946-949,共4页
Global Traditional Chinese Medicine
基金
国家自然科学基金(81473659)
北京中医药大学校级自主课题(2015-JYB-XS180)
关键词
慢性阻塞性肺疾病
肺络
微型癥瘕
分子生物学
气道重构
Chronic obstructive pulmonary disease
Feiluo
Micro-zhengjia
Molecular biol ogy
Airway remodeling
