摘要
目的应用Meta分析的方法分析心可舒胶囊治疗冠心病心绞痛的疗效及其安全。方法电脑查阅Cochrane试验资料库（2016年第1期）、Embase（1966年至2016年3月）、Pubmed（1966年至2016年3月）、中国学术文献总库（CNKI）（1979年至2016年3月）、中文科技期刊数据库（1989年至2016年3月）、万方数字期刊库（1981年至2016年3月）,根据入选与剔除原则筛选文献、评价文献质量,从文献中提取相关数据,应用Rev Man 5.3软件对提取的数据进行Meta分析。结果初步检索出109篇文献,根据选取标准共有4篇文献符合。从症状疗效来分析：χ~2=0.02,df=3,P=1.00,合并OR=4.30,95%CI[2.74,6.73],Z=6.36（P〈0.00001）;从心电图疗效来分析：χ~2=0.57,df=3,P=0.90,合并OR=2.76,95%CI[1.88,4.07],Z=5.14（P〈0.00001）。结论心可舒通胶囊治疗冠心病心绞痛在缓解症状及改善心电图方面效果显著,且无明显不良反应。
Objective：To analyze the efficacy and safety of Xinkeshu capsule on unstable angina（UA）.Methods：The following data bases were researched：Cochrane Central Register of Controlled Trials（Issue 1,2016）,EMbase（1966 to March 2016）,Pubmed（1966 to March 2016）,CNKI（1979 to March 2016）,CBM（1989 to March2016）,and Wanfang（1981 to March 2016）.According to selection and elimination principle,literature was selected and evaluated.Related data was drawn and Meta-analyzed with Rev Man 5.3 software.Results：A total of109 articles were found,4 of which were finally included.Therapeutic effects of angina pectoris were selected as the study indices：χ~2=0.02,df=3,P = 1.00,OR=4.30,95%CI[2.74,6.73],Z = 6.36（P 0.00001）.ECG were selected as the study indices：χ~2=0.57,df=3,P = 0.90,and OR=2.76,95%CI [1.88,4.07],Z = 5.14（P 0.00001）.Conclusion：Xinkeshu capsule is effective and safe on unstable angina and relief of symptoms and improvement of electrocardiogram,without no obvious adverse reactions.
出处
《中国中医急症》
2016年第8期1477-1479,共3页
Journal of Emergency in Traditional Chinese Medicine
基金
吉林省科技厅项目(200905138)
关键词
心可舒胶囊
冠心病
心绞痛
META分析
Xinkeshu capsule
Coronary heart disease
Unstable angina
Meta-analysis
