摘要
目的：通过随机、对照的临床试验,评价多媒体训练系统治疗儿童弱视的有效性和安全性。方法：选取203例（253眼）3~12岁弱视儿童,随机分为试验组和对照组。试验组100例（170眼）,对照组103例（183眼）。试验组通过多媒体训练系统进行治疗,对照组通过传统弱视治疗方法进行治疗。治疗3、6个月后复查矫正视力。通过比较两组的弱视治疗效果来评价多媒体训练系统治疗儿童弱视的有效性和安全性。结果 ：治疗6月后,试验组和对照组的总有效率分别为74.1%和52.5%,两组差异有统计学意义（P〈0.001）;试验组中屈光不正性弱视的有效率为80.5%,高于对照组（50.8%）,两组差异有统计学意义（P〈0.001）;试验组中3~6岁和7~12岁的有效率分别为80.8%和58.0%,高于对照组的54.9%和43.9%,差异均有统计学意义（P〈0.001和P〈0.05）。结论：多媒体训练系统治疗弱视的疗效明显优于传统弱视治疗方法,对屈光不正性弱视较好,对各年龄组均有较好疗效。
Objective To assess the efficacy and safety of multimedia visual training system for amblyopic children through a randomized, controlled clinical trial. Methods A total of 203 amblyopic children（253eyes） ages 3 to 12 years were randomly divided into a study group（100 patients, 170 eyes） and a control group（103 patients, 183 eyes）. The study group received multimedia training system; while the control group received conventional integrated therapies. Best corrected visual acuity was examined 3 and 6 months after treatment. The efficacy and safety of multimedia visual training system for amblyopic children was assessed by comparing the effect of treatment in both groups. Results 6 months after treatment, the total effectiveness rate was 74.1% in the study group and 52.5% in the control group, and there was a statistical difference（P 0.0001）. The effectiveness rate for refractive amblyopia was higher in the study group than in the control group（80.5% vs. 50.8%）,and there was a significant difference（P 0.001）. As compared with the effectiveness rate for different ages,the subgroups of 3 to 6 years and 7 to 12 years in the study group was 80.8% and 58.0%, much higher than those in the control group（54.9% and 43.9%）, and there were statistical differences（P 0.001 and P 0.05）.Conclusions The efficacy of multimedia visual training system is superior to that of the traditional treatment,especially for refractive amblyopia. It is effective in all age groups.
出处
《实用医学杂志》
CAS
北大核心
2016年第16期2652-2655,共4页
The Journal of Practical Medicine
基金
广东省东莞市科技计划项目(编号:20131051010229)
关键词
弱视
多媒体训练系统
传统方法
视力
Amblyopia
Multimedia visual training system
Traditional methods
Visual acuity
