摘要
目的观察茵栀黄口服液联合间歇蓝光照射治疗新生儿病理性黄疸的疗效。方法将96例新生儿病理性黄疸患儿随机分为对照组和治疗组,各48例。对照组给予输液、静脉输注白蛋白、静脉注射维生素C、口服维生素B2等常规治疗,并进行蓝光照射,4 h/次,间歇2 h,4次/d,治疗组在对照组治疗方法的基础上口服茵栀黄口服液,5 m L/次,2次/d。治疗7 d后统计2组患儿的临床疗效。结果对照组总有效率为89.6%,治疗组为97.9%,经统计学分析,差异有统计意义(P<0.05)。治疗后第1,3,7天,2组胆红素水平均逐渐下降,与同组治疗前比较,差异有统计意义(P<0.05);且治疗组胆红素水平下降幅度大于对照组,经统计学分析,差异有统计意义(P<0.05)。治疗组患儿的胆红素水平恢复至正常时间及住院时间明显短于对照组,经统计学分析,差异有统计意义(P<0.05)。结论茵栀黄口服液联合间歇蓝光照射可明显缩短新生儿病理性黄疸的治疗时间,提高临床疗效。
Objective To observe the effect of Yinzhihuang Koufuye combined with intermittent blue light irradiation in treating neonatal pathological jaundice. Methods 96 cases of neonatal pathological jaundice were ran- domly divided into control group and treatment group, 48 cases in each group. Patients in the control group were given intravenous transfusion, albumin infusion, intravenous injection of vitamin C, oral administration of vitamin B2, and treated with blue light irradiation, 4 hours/time, intermittent 2 hours, 4 times/d. Treatment group was additionally given Yinzhihuang Koufuye, 5 mL/time, 2 times/d. Clinical effect of 2 groups after 7 days treatment was analyzed. Results The total effective rate was 89.6% in the control group and 97.9% in the treatment group （P〈 0.05）. After the treatment of 1, 3, 7 days, bilirubin level was decreased gradually in both groups （P〈0.05）. The level of bi-lirubin decreased more significantly than that of the control group （P〈0.05）. The time for the level of bilirubin in the treatment group to restore to normal and hospital stays were significantly shorter than that in the con- trol group, and the difference was statistically significant （P〈0.05）. Conclusion Yinzhihuang Koufuye with intermittent blue light irradiation in the treatment of neonatal pathological jaundice, can significantly shorten the treatment time and improve clinical curative effect.
出处
《中医儿科杂志》
2016年第4期55-57,共3页
Journal of Pediatrics of Traditional Chinese Medicine
关键词
病理性黄疸
新生儿
茵栀黄口服液
蓝光照射
疗效观察
pathological jaundice
neonatal
Yinzhihuang Koufuye
phototherapy
clinical observation
