摘要
目的:分析温下健脾法改善重度脓毒症患者胃肠功能障碍的临床效果。方法:连续选择90例重度脓毒症患者采用随机、双盲、对照方法将其分为三组,每组30例,即中西医治疗组(附桂姜黄汤配合常规西医治疗),对照1组(乳果糖配合常规西医治疗)和对照2组(常规西医治疗),对比治疗效果。结果:中西医治疗组的NRS2002和APACHEⅡ评分均较治疗前明显下降,显著低于其他两组(P<0.05)。各组治疗前后的BMI、体重、中臂围和皮褶厚度的比较,差异均无统计学意义(P>0.05)。治疗后各组的HGB、ALB、前白蛋白和转铁蛋白水平均较治疗前增加,且中西医治疗组改善的更明显(P<0.05)。中西医治疗组的平均ICU时间和28d死亡率均显著低于其他两组(P<0.05)。结论:温下健脾法可以改善重度脓毒症患者的胃肠功能障碍,有较大的临床应用价值。
Objective ：To study the effect of warming spleen method improving gastrointestinal dysfunction in patients with severe sepsis .Method ：A total of 90 consecutives were divided into three groups and each of 30 cases ,the combined group（Fugui Jianghuang decoction ＋ common medical treatments ） ,compare one group （lactulose ＋ common medical treatments）and compare two group （common medical treatments ）by a random ,double-blind ,compare method ;then to compare effects differences .Results ：The NRS2002 and APACHE Ⅱ scores in combined group were lower than be-fore treatment ,thus significantly lower than the other two groups （P〈 0 .05） . The BMI ,body weight ,middle arm circ-umference ,skin fold thickness values in the three groups were no statistical differences （P〉 0 .05） . The HGB ,ALB ,pre-albumin and transferring levels in the three groups were all higher than before ,what’s more ,they in combined group were significantly higher than the others（P〈 0 .05） . And the in-ICU days and mortality for 28 days in combined group were significantly less（P〈 0 .05） . Conclusion ：Warming spleen method could furtherly improve gastrointestinal dysfunction in patients with severe sepsis .
出处
《陕西中医》
2016年第8期939-941,共3页
Shaanxi Journal of Traditional Chinese Medicine
基金
广东省佛山市卫生和计划生育局医学科研课题(20160004)
关键词
脓毒症/中西医结合疗法
温下
@附桂姜黄汤
Sepsis/integrated
Chinese traditional and western medicine therapy
Warm
purgation Fugui Jianghuang decoction
