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B和T淋巴细胞弱化因子在感染性疾病中的免疫作用 被引量:8

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摘要 B和T淋巴细胞弱化因子(B and T lymphocyte attenuator,BTLA)是继程序性死亡因子-1(programmed death-1,PD-1)、细胞毒性T细胞活化抗原4(cytotoxic T lymphocyte Antigen-4,CTLA-4)后发现的第三个属于CD28免疫球蛋白超家族的负性共刺激分子,抑制或下调T细胞的活化和细胞因子的产生。BTLA参与不同感染性疾病的发生和发展。本文根据国内外的研究进展,对BTLA在感染过程中的免疫作用做简要综述。
作者 宁书蔚 臧彬
出处 《实用检验医师杂志》 2016年第2期106-110,共5页 Chinese Journal of Clinical Pathologist
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参考文献35

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