摘要
目的分析人乳头状瘤病毒(HPV)感染与宫颈糜烂的关系并探讨α-干扰素栓治疗宫颈糜烂的临床效果,为宫颈糜烂的临床治疗提供参考依据。方法选取2013年5月-2015年1月于医院就诊的234例宫颈糜烂患者作为研究对象,将患者随机分对照组和治疗组,各117例;对照组采用微波治疗,治疗组在对照组基础上加用α-干扰素栓辅助治疗,比较两组患者治疗有效率,数据采用SPSS 16.0软件进行统计分析。结果治疗组总有效率为92.3%,显著高于对照组患者的80.3%,差异有统计学意义(P<0.05);治疗组复发率为10.3%,显著低于对照组的26.5%,组间比较差异均有统计学差异(P<0.05)。结论 HPV感染与宫颈糜烂的病情严重程度密切相关,α-干扰素栓辅助微波法治疗宫颈糜烂疗效显著,复发率低。
OBJECTIVE To investigate the relationship between HPV infection and cervical erosion and to explore the clinical effect of antivirus therapy,so as to provide references for clinical treatment of cervical erosion.METHODS A total of 234 patients with cervical erosion who visited hospital from May 2013 to Jan.2015 were selected,and randomly divided into control group and treatment group,with 117 cases in each group.Patients in control group received microwave treatment and in treatment group received IFN-αsuppositories on the basis of control group.The clinical efficacies of the two groups were compared,and the data were analyzed by SPSS 16.0.RESULTS The total effective rate of treatment group was 92.3%,significantly higher than 80.3% of control group（P〈0.05）.The recurrence rate of treatment group was 10.3%,significantly lower than 26.5% of control group（P〈0.05）.CONCLUSION The levels and types of cervical erosion are closely related to the infection of HPV.IFN-αsuppositories combined with microwave treatment has significant efficacy,with low recurrence rate.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2016年第15期3525-3527,共3页
Chinese Journal of Nosocomiology
基金
浙江省中医药科技计划基金资助项目(2009CA070)
