摘要
2型糖尿病患者大血管并发症的患病率高于非糖尿病人群3~4倍,其共同病理基础是动脉粥样硬化。visfatin是由内脏脂肪组织分泌的脂肪因子家族中的新成员,与缺氧、胰岛素抵抗、糖脂代谢、炎症及免疫调节等密切相关,其在2型糖尿病状态下动脉粥样硬化的发生、发展和转归中的作用日益受到关注。本文就visfatin与糖尿病大血管病变关系的研究进展作一综述。
The incidence of macrovascular complications is 3 to 4 times higher in patients with type 2 diabetes mellitus than that in patients with no diabetes mellitus, with the common pathological basis of atherosclerosis. Visfatin is a new member of the fat factor family secreted by visceral adipose tissue, being closely correlated with hypoxia, insulin resistance, glucose and lipid metabolism, inflammation and immune. More and more researches focus on its role in the occurrence, development and turnover of atherosclerosis in patients with type 2 diabetes mellitus. This paper reviews the relationship between visfatin and macrovascular diseases in patients with diabetes mellitus.
出处
《中华实用诊断与治疗杂志》
2016年第8期732-734,共3页
Journal of Chinese Practical Diagnosis and Therapy
基金
黑龙江省教育厅科学技术研究项目(12531318)
关键词
2型糖尿病
内脂素
动脉粥样硬化
Type 2 diabetes mellitus
visfatin
atherosclerosis
