摘要
目的：分析无创呼吸机联合吸氧在慢性阻塞性肺病（COPD）伴随慢性Ⅱ型呼吸衰竭患者中的应用效果。方法：选取2005年1月～2014年1月间在我院治疗的48例COPD伴随慢性Ⅱ型呼吸衰竭患者，随机分为观察组和对照组各24例，在常规治疗基础上，对照组患者实施鼻导管吸氧，观察组患者实施无创呼吸机机械通气联合吸氧治疗，比较两组患者动脉血气分析结果、肺功能、患者依从性以及不良反应发生率差异。结果：治疗后，两组患者动脉血气分析结果均趋于正常（P〈0．05），但观察组患者更明显（P〈0．05）；两组患者肺功能均明显改善（P〈0．05），但观察组患者肺功能明显优于对照组（P〈0．05）；差异具有统计学意义。两组患者不良反应发生率及依从性均无统计学差异（P〉0．05）。结论：无创呼吸机联合吸氧可明显改善慢性阻塞性肺病伴慢性Ⅱ型呼吸衰竭患者预后质量。
OBJECTIVE ： To observe the clinical effect of non - invasive positive pressure ventilation and reintroducing oxygen on chronic obstructive pulmonary disease combined with type - Ⅱ respiratory failure. METHODS： 48 patients with chronic obstructive pulmonary disease combined with chronic type - Ⅱ respiratory failure in our hospital from January 2005 to January 2014 were selected. They were randomly divided into control group （n =24） and observation group （n =24）. On the basis of routine treatment, control group received nasal catheter oxygen therapy and observation group received non - invasive mechanical ventilation combined with rein- troducing oxygen therapy. The arterial blood gas analysis result, pulmonary function, compliance and adverse reaction rate were com- pared. RESULTS ： After treatment the arterial blood gas analysis results of the patients in both groups tended to be normal （ P 〈 0. 05 ） , but the ones in observation group were more obviously （ P 〈 0. 05 ）. The pulmonary function of the patients in both groups im- proved significantly （ P 〈 0. 05 ）, while the one in observation group was better than that in control group （ P 〈 0. 05 ）. There were no significant difference in the compliance score and adverse reaction rate in both groups. CONCLUSION： The prognosis quality of the patients with chronic obstructive pulmonary disease combined with chronic type - Ⅱrespiratory failure can be obviously improved by the treatment of non - invasive positive pressure ventilation combined with reintroducing oxygen.
出处
《国际老年医学杂志》
2016年第4期163-165,共3页
International Journal of Geriatrics
基金
2015年张家口市科技计划自筹项目（1521081D）
关键词
无创呼吸机
吸氧
慢性阻塞性肺病
慢性Ⅱ型呼吸衰竭
临床效果
Non - invasive positive pressure ventilation
Reintroducing oxygen
Chronic obstructive pulmonary disease
Chron-ic type - Ⅱ respiratory failure
