摘要
目的：探讨影响ICU感染性休克患者预后的相关因素。方法回顾性分析2007-07-2015-07入住我院ICU 200例感染性休克患者的临床资料，其中死亡患者68例，非死亡患者132例。搜集、整理两组患者相关资料，分别采用单因素与多因素分析的方法确定影响ICU感染性休克患者预后的相关因素。结果经Pearson单因素分析发现，死亡组与非死亡组年龄、APACHEⅡ评分、是否有合并症（真菌感染、ARDS、AKI、DIC）、血小板减少、抗凝治疗比较差异均有统计学意义（P＜0.05）。将相关因素进行Logistic回归分析得出，年龄（OR 2.502，95%CI 1.392-4.430， P＝0.023）、APACHEⅡ评分＞20分（OR 2.129，95%CI 1.188-4.732，P＝0.029）、合并真菌感染（OR 3.092，95% CI 1.335-6.731，P＝0.029）、合并ARDS（OR 2.627，95% CI 1.297-5.032，P＝0.011）、合并AKI（OR 3.829，95%CI 1.615-5.592，P＝0.001）、抗凝治疗（OR 0.293，95%CI 0.140-0.627，P＝0.001）影响感染性休克患者的预后。结论影响ICU感染性休克患者预后的相关因素较多，应将这些因素进行仔细观察，从而为采取防止措施，有效改善患者预后状况提供依据。
Objective To investigate the prognostic factors in patients with septic shock in ICU. Methods The clinical data of 200 patients with septic shock in our hospital from July 2007 to July 2015 were retrospectively analyzed,including 68 patients death and 132 patients non death. First of all, the relevant data of the two groups were collected and analyzed,and then the correlation factors of the prognosis of patients with ICU were determined by single factor and multiple factor analysis. Results①The differences in age, APACHEⅡscore, complication（Fungus infection, ARDS, DIC, AKI）,thrombocytopenia, anticoagulant therapy were statistically significant （P〈0.05） by Pearson single factor analysis. ②The related factors were analyzed by Logistic Regression Model, showing that age （OR 2.502, 95% CI 1.392-4.430, P=0.023）,APACHEⅡ scores〉20（OR 2.129, 95% CI 1.188-4.732, P=0.029）,combined Fungus infection（OR 3.092, 95%CI 1.335-6.731, P=0.029）,combined ARDS （OR 2.627, 95% CI 1.297-5.032, P=0.011）, combined AKI（OR 3.829,95% CI 1.615-5.592, P=0.001）,anticoagulant therapy（OR 0.293,95%CI 0.140-0.627, P=0.001）. Conclusion There are many factors that affect the prognosis of patients with septic shock in patients with ICU,and these factors should be carefully observed,so as to take preventive measures to effectively improve the prognosis of patients.
出处
《中国急救医学》
CAS
CSCD
北大核心
2016年第7期581-584,共4页
Chinese Journal of Critical Care Medicine
基金
广东省自然科学基金（2015A030313581）
广东药学院科技处一附属第一医院联合自然科学培育基金项目（GYFYLH201320）
关键词
感染性休克
预后
影响因素
合并症
脓毒症
Septic shock
Prognosis
Influencing factors
Complication
Sepsis
