摘要
随着近几年双抗原夹心法定量检测抗-HBc的发展和应用,人们对抗-HBc在反映机体抗病毒能力方面的认识越来越多。简述了抗-HBc目前常用的检测方法和抗-HBc检测的新趋势,总结了血清中抗-HBc的水平与病毒抗原和机体的免疫应答状态有关,以及在抗病毒治疗前检测基线抗-HBc可有效预测抗病毒疗效等方面取得的研究进展。指出仍需深入研究抗-HBc在临床中的应用价值。
With the development and application of the double antigen sandwich method for quantification of hepatitis B core antibody（ HBcAb） in recent years,there is increasing knowledge of the ability of HBcAb to reflect the body＇s anti- viral capability. This article introduces the commonly used measurement methods for HBcAb and the new trends in HBcAb measurement and summarizes the association of serum HBcAb level with viral antigen and the body＇s immune response,as well as research advances in effective prediction of antiviral effect with baseline HBcAb measurement before antiviral therapy. It is also pointed out that the clinical application of HBcAb needs further investigation.
出处
《临床肝胆病杂志》
CAS
2016年第7期1403-1405,共3页
Journal of Clinical Hepatology
基金
河北省科技成果重点推广计划(13277765D)
关键词
肝炎抗体
乙型
综述
hepatitis B antibodies
review
