摘要
目的探讨代谢综合征（MS）对颈动脉内中膜厚度（CIMT）影响的性别差异。方法选取2013-10-08至2014-02-25于皖北煤电集团总医院参加体检人群593例。受试者禁食8～12 h后,进行常规体检和生化指标检测;由经过培训的两名专业医师在短轴切面测量CIMT,取平均值。结果男性MS患病率为29.8%（105/353）,女性MS患病率为24.6%（59/240）,差异无统计学意义（χ2=1.087,P〉0.05）。男性、绝经前后女性中,不同MS组分数者CIMT比较,差异均有统计学意义（F=12.240、8.850、9.510,P〈0.001）。男性、绝经前后女性0、1项组分者CIMT比较,差异有统计学意义（F=8.890、8.620,P〈0.001）,其中,男性、绝经后女性0、1项组分者CIMT大于绝经前女性,差异有统计学意义（P〈0.05）。男性、绝经前后女性≥3项组分者CIMT比较,差异有统计学意义（F=0.670,P=0.002）,其中,男性、绝经后女性≥3项组分者CIMT大于绝经前女性,绝经后女性CIMT大于男性,差异有统计学意义（P〈0.05）。Logistic回归分析显示,MS是女性CIMT增厚的危险因素〔OR=5.611,95%CI（1.398,22.632）,P〈0.05〕,而未发现与男性CIMT增厚有关〔OR=1.091,95%CI（0.906,1.314）,P〉0.05〕。结论 MS对CIMT的影响存在性别差异,MS对女性CIMT的影响更显著。
Objective To investigate the difference of the influence of metabolic syndrome （MS） on carotid intima - media thickness （CIMT） between two genders. Methods We enrolled 593 people who received physical examination in the General Hospital of Wanbei Coal Group from October 8, 2013 to February 25, 2014. After fasting for 8 to 12 hours, the subjects received conventional physical examination and biochemical criterion detection. Two professional physicians who had been trained measured CIMT by short axis, and average value was calculated. Results The MS prevalence was 29.8% （ 105/353 ） for males and 24. 6% （59/240） for females, without significant difference between them （ ~2 = 1. 087, P 〉 0. 05）. Among males and females before and after menopause, subjects with different number of MS components were significantly different in CIMT （ F = 12. 240, 8. 850, 9. 510 ; P 〈 0. 001 ）. When having no component or one component, males and females before and after menopause were significantly different in CIMT （ F = 8. 890, 8. 620 ; P 〈 0. 001 ） ; males and females after menopause were higher than females before menopause in CIMT （P 〈 0. 05 ）. When having ≥3 components, males and females after menopause were significantly different in CIMT （ F = 0. 670, P = 0. 002） ; males and females after menopause were higher than females before menopause in CIMT, and females after menopause was higher than males in CIMT （ P 〈 0. 05 ）. Logistic regression analysis showed that the MS was a risk factor for the increase in CIMT thickness of female [ OR = 5. 611, 95% CI （1. 398, 22. 632）, P 〈 0. 05 J, while no correlation was found between the MS and the increase in CIMT thickness of males [ OR = 1. 091, 95% CI （0. 906, 1. 314）, P 〉 0. 05 1- Conclusion Difference exists in the influence of MS on CIMT between different genders, and MS has more significant iiffluence on CIMT in females.
出处
《中国全科医学》
CAS
CSCD
北大核心
2016年第20期2395-2398,共4页
Chinese General Practice
关键词
代谢综合征
颈动脉内中膜厚度
性别
Metabolic syndrome
Carotid intima-media thickness
Gender
