期刊文献+

流感抗病毒药物覆盖率与人均剂量的关系 被引量:1

Relationship Between Influenza Antiviral Drug Coverage and the Dose of Per Capita
下载PDF
导出
摘要 在舱室模型SEITINR(易感者-潜伏期-治疗/未治疗患者-痊愈者)基础上,且疫情得到成功控制的条件下,研究了药物覆盖率与人均分发药物量之间的关系.采用实际疫情数据以及相关文献估算参数,进行数值拟合.结果发现,在药物覆盖率达到68%,人均分发药物量达8剂时,可以成功控制流感爆发.这可为资金条件、抗病毒药物储存量等因素制约下,以有效控制疫情为前提,用抗病毒药物治疗流感提供一个最优疾控方案,以便在流感疫情爆发初期及早治疗,减少不必要的财物浪费. With the compartmental model SEITINR (susceptible people-latent period-treated/untreated patients-recovered people) and the successful control of epidemic, the relationship between the drug coverage and per capita amount of distri- bution of drugs was studied. By estimating the parameters of actual epidemic data and related literature and doing numeri- cal fitting, it shows that when the drug coverage reached 68%, per capita distribute drugs are up to 8 doses, it is easy to control the flu outbreak successfully. That presents an effective disease control program with influenza antiviral treatment even under restricted factors, such as funding conditions and antiviral stockpiles, on the premise of effective control of epi- demic situation, thus provides early treatment to reduce the waste of unnecessary possessions.
作者 白文勇
出处 《宜宾学院学报》 2016年第6期82-85,共4页 Journal of Yibin University
关键词 舱室模型 流感 抗病毒药物 compartmental model influenza antiviral treatment
  • 相关文献

参考文献13

  • 1BEIGEL J H, FARRAR J, HAN A M, et al. Avian influenza A (HSNI) infection in humans[J]. New England Journal of Medicine, 2005, 353(13): 1374-1385. doi:lO.lO56/NEJMra052211. 被引量:1
  • 2YARMAND H, IVY J S, ROBERTS S D. Identifying optimal mitigation strategies for responding to a mild influenza epidemic[J]. Simulation, 2013, 89(11): 1400-1415. doi:10.1177/ 0037549713505334. 被引量:1
  • 3WEBBY R J, WEBSTER R G. Are we ready for pandemic influ, enza?[J]. Science, 2003, 302(5650): 1519-1522. doi:10.1126/science. 1090350. 被引量:1
  • 4TREANOR J J, HAYDEN F G, VROOMAN P S, et al. Efficacy and safety of the oral neuraminidase inhibitor oseltamivir in treating acute influenza: a randomized controlled trial[J]. Jama, 2000, 283(8): 1016-1024. 被引量:1
  • 5ARINAMINPATHY N, MCLEAN A R. Antiviral treatment for the control of pandemic influenza: some logistical constraints [J]. Journal of the Royal Society Interface, 2008, 5(22): 545553. 被引量:1
  • 6GANI R, HUGHES H, FLEMING D, et al. Potential impact of antiviral drug use during influenza pandemic[J]. Emerg Infect Dis, 2005, 11(9):1355-1362. 被引量:1
  • 7BERETI'A E, TAKEUCHI Y. Global stability of an SIR epidemic model with time delays[J]. Journal of Mathematical Biology, 1995, 33(3): 250-260. doi:lO.lOO7/BFO0169563. 被引量:1
  • 8VAN DEN DRIESSCHE P, WATMOUGH J. Reproduction numbers and sub-threshold endemic equilibria for compart-mental models of disease transmission[J]. Mathematical biosciences, 2002, 180(1): 2948. doi: 10.1016/S00255564(02) 00108,6. 被引量:1
  • 9TOWERS S, GEISSE K V, ZHENG Y, et al. Antiviral treatment for pandemic influenza: Assessing potential repercussions using a seasonally forced SIR model[J]. Journal of theoretical biology, 2011, 289: 259-268. doi:10.1016/i.itbi.2011.08.011. 被引量:1
  • 10CHOWELL G, NISHIURA H, BETrENCOURT L M A. Comparative estimation of the reproduction number for pandemic influenza from daily case notification data[J]. Journal of the Royal Society Interface, 2007, 4(12): 155-166. 被引量:1

同被引文献4

引证文献1

二级引证文献2

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部