摘要
目的探讨复发性急性胰腺炎（RAP）的病因和临床特征。方法急性胰腺炎（AP）病人887例,其中RAP病人124例,单发AP病人763例,采用计算机随机抽样的方法选取247例单发AP为单发组,对两组病人临床资料进行分析。结果单发组男142例,女105例;复发组男78例,女46例,两组性别比例差异无统计学意义（P〉0.05）。复发组年龄小于单发组,差异有统计学意义（t=3.792,P〈0.05）。与单发组比较,复发组住院天数延长,三酰甘油水平升高,并发症发生率增高,差异有显著性（t=4.842、3.923,χ2=17.74,P〈0.05）。RAP病因为胆源性40例,高脂血症33例,乙醇性12例,暴饮暴食8例,特发性22例,其他9例。Logistic逐步回归分析显示,只有高脂血症对AP的复发有影响。结论 RAP好发于中年男性,胆源性和高脂血症为常见的病因,且高脂血症对AP的多次复发有重要影响。
Objective To investigate the etiology and clinical features of recurrent acute pancreatitis（RAP）. Methods A total of 887 AP patients were enrolled.Of whom,124 were RAP,and 763 were single AP（SAP）.Using a computer random sampling method,247 cases of SAP were selected to be served as SAP control group.The clinical data of patients in the two groups were analyzed. Results In the SAP group,142 were male and 105,in RAP group,78 were male and 46 were female,the difference in gender between the two groups was not significant（P〉0.05）.The age of patients in RAP group was younger than those in the SAP group,the difference being statistically significant（t=3.792,P〈0.05）.Compared with the SAP group,the length of hospital stay in RAP patients prolonged,the level of triacylglycerol elevated and complications increased（t=4.842,3.923;χ2=17.74,P〈0.05）.The causes of RAP were as follows：biliary（40cases）,hyperlipidemia（33cases）,alcoholic（12cases）,binge overeating（8cases）,idiopathic（22cases）and others（9cases）.Logistic stepwise regression analysis indicated that only hyperlipidemia impacted the recurrence of AP. Conclusion Recurrent acute pancreatitis more commonly occurs in middle-aged men,biliary origin and hyperlipidemia being the frequently seen causes of the disease.Hyperlipidemia plays an important effect on multiple recurrence of acute pancreatitis.
出处
《青岛大学医学院学报》
CAS
2016年第3期335-337,共3页
Acta Academiae Medicinae Qingdao Universitatis
关键词
胰腺炎
复发
回归分析
pancreatitis
recurrence
regression analysis
