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EndMT在血管重塑中的作用及相关信号通路 被引量:5

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摘要 肺血管重塑是肺高压的主要特征。内皮细胞可由血管内膜层迁移并转化为间充质细胞或平滑肌样细胞,这一过程称为内皮间充质转化(EndMT),可引起血管重塑。与EndMT相关的信号通路主要有转化生长因子β、Wnt、Notch等。抑制EndMT发生有望成为延缓或阻止肺高压进展的一种治疗手段。
出处 《江苏医药》 CAS 2016年第12期1384-1386,共3页 Jiangsu Medical Journal
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