摘要
连续血糖检测对于糖尿病等疾病的诊治意义重大,近年来国内外很多机构都进行了该方面的研究.由于组织液中的葡萄糖浓度与血糖浓度有很好的相关性,基于组织液测量的微创伤血糖检测技术对人体创伤小,且能实现连续的血糖检测,在技术上容易突破,能够较快地在临床上实现,故而受到广泛关注,近年来发展迅猛.按照检测手段的不同,基于组织液测量的微创伤血糖检测技术主要分为皮下植入式和透皮抽取式两种,故本文重点从这两个方面分别阐述了近年来国内外微创伤血糖连续检测技术及仪器的研究进展,并指出了其现阶段存在的主要问题和未来的一些发展方向.
Continuous blood glucose monitoring is critical for the treatment of diabetes ; and many organizations have been working on this field recently. Glucose concentrations in interstitial fluid are closely related to those in the blood. Continuous minimally invasive blood glucose monitoring technology based on analysis of interstitial fluid develops rapidly because it relieves the suffering of patients and is technically easy to realize, which, in turn, is suitable for clinical applications. Thus, in this field, a majority of work has been made based on the measurement of glucose concentration in interstitial fluid. According to the different detection methods, most of these work can be divided into two categories： those using subcutaneous implantation method and those using transdermal extraction method. This paper reviews the recent development of minimally invasive blood glucose measuring technology and instruments through these two categories. The challenges remained and the future research directions are presented as well.
出处
《纳米技术与精密工程》
CAS
CSCD
北大核心
2016年第4期269-277,共9页
Nanotechnology and Precision Engineering
关键词
血糖连续检测
微创伤
组织液
皮下植入式
透皮抽取
continuous blood glucose monitoring
minimal invasion
interstitial fluid
subcutaneous implantation
transdermal extraction
