摘要
目的探讨MRI优化的三维容积内插快速扰相梯度回波(3D-Radial-VIBE)序列在胎儿神经系统检查中的应用价值。方法收集超声诊断或疑似胎儿颅脑异常的中晚期妊娠妇女20名,对其分别行二维快速小角度激励扰相梯度回波序列(2D-FLASH)和3D-Radial-VIBE序列扫描,然后对2个序列图像显示的胎儿颅脑26个正常解剖结构分别进行评分,并进行统计学分析。结果 26个胎儿颅脑解剖结构中,22个结构的3D-Radial-VIBE序列与2D-FLASH序列评分的差异有统计学意义(P均<0.05)。与2D-FLASH序列比较,3D-Radial-VIBE序列运动伪影较小,胎头、胎盘、内脏等均显示较好,尤其可清晰显示胎头结构以及灰白质、髓鞘化过程。3D-Radial-VIBE序列示20胎正常颅后窝静脉窦区均呈低信号,而2D-FLASH示15胎呈高信号,假阳性率为75.00%(15/20)。与2D-FLASH序列比较,3D-Radial-VIBE序列显示的出血灶更清晰。3D-Radial-VIBE序列显示顶叶灰质与白质的信号对比度、颞叶灰质与白质的信号对比度及颞叶灰质与板障的信号对比度均高于2D-FLASH序列(P均<0.05)。结论 3D-Radial-VIBE序列扫描过程中无需屏气,抗运动伪影效果好,对神经核团、髓鞘化过程及出血灶的显示具有明显优势。
Objective To explore the application value of MRI three-dimensional radial volume interpolated body examina- tion （3D-Radial-VIBE） sequence in fetus nervous system examination. Methods Totally 20 middle and late pregnant women who were diagnosed or suspected fetal brain abnormality by ultrasound were collected. Two-dimensional fast low angle shot （2D-FLASH） sequence and 3D-Radial-VIBE sequence were carried out respectively. The twenty-six normal structures of fetus brain on collected images of the 2 sequences were evaluated and analyzed statistically. Results In twenty six structures, the differences of the score of twenty-two structures between 3D-Radial-VIBE and 2D-FLASH sequence were all statistically significant （all P〈0.05）. Compared with 2D-FLASH sequence, the motion artifact of 3D-Radial- VIBE sequence was less, and then fetal head, placenta and internal organs were shown preferably, especially fetal head structure, gray matter and myelination process were clearly shown. Normal posterior fossa sinus area in 20 fetus was low signal in 3D-Radial-VIBE sequence, but 15 fetus were high signal in 2D-FLASH sequence, and the false positive rate was 75.00% （15/20）. Compared with 2D-FLASH sequence, the ranges of hemorrhage lesion was more clear in 3D-Radial- VIBE sequence. The contrast ratio of gray matter and white matter in parietal lobe and temporal lobe, gray matter and sub- plate in temporal lobe were higher in 3D-Radial-VlBE sequence than those of 2D-FLASH （all P^0. 05）. Conclusion 3D- Radial-VIBE sequence scan is without hold breath, better in resistance to motion artifact, and it has obvious advantages in showing nerve nuclei, myelination process and hemorrhage lesion.
出处
《中国医学影像技术》
CSCD
北大核心
2016年第7期1119-1123,共5页
Chinese Journal of Medical Imaging Technology
基金
湖南省科技计划项目基金(2014RS4012)
