摘要
目的:基于中医传承辅助平台(TCMISS)V2.5和SPSS软件,分析中医药治疗胶质瘤的组方用药规律。方法:收集1984年1月—2015年10月以来中医药治疗胶质瘤的文献,建立方剂数据库,分析药物的频次和关联规则,对方剂中药物配伍规律进行分析;并对药物的性味、归经进行聚类分析。结果:共筛选出中医药治疗胶质瘤的方剂88首,涉及不同的中药共232种。确定了12个核心药物配伍,六首新方剂和八个高频药群。结论:治疗胶质瘤方剂以平肝熄风、破瘀散结,补气养血和健脾化湿为主,并以辛、苦、甘味,归肝、肾、脾和肺经的中药居多,为中医药临床治疗胶质瘤提供依据。
Objective ： To analyze the rules of formula medication for glioma based on traditional Chinese medicine inheritance support system （TCMISS） V2.5 and statistical product and service solutions （SPSS）. Methods ： The literature for the treatment of glioma was collected from January 1984 to October 2015. The formulas database was established; the frequency and the association rules of herbs were analysed; the compatibility of medicines in the prescription was analysed ; the properties, flavors and meridian tropism of herbs were carried out by systematic cluster analysis method. Resuits： 88 formulas of traditional Chinese medicine treatment of glioma were screened and a total of 232 kinds of herbs were involved. 12 core herbs combination, six new prescriptions and eight high - frequency herbs groups of similar prop- erties were established. Conclusion： The major formulas for the treatment of glioma have the actions of suppressing hyperactive liver for calming endogenous wind, drastically removing blood stasis and static blood, invigorating spleen for eliminating dampness and benefiting Qi and nourishing blood, which especially belong to the pungent, bitter and sweet flavor and meridian tropism of the liver, kidney, spleen and lung channels. The results will provide a basis for TCM clinical treatment of glioma.
出处
《中医药学报》
CAS
2016年第3期12-15,共4页
Acta Chinese Medicine and Pharmacology
基金
北京市中医药科技基金面上项目(JJ2013-007)
北京市属高等学校高层次人才引进与培养计划-长城学者项目(CIT&TCD20140329)
