摘要
目的:分析磁共振弥散加权成像(DWI)和波普分析(MRS)在脑胶质瘤的临床应用。方法:选取2010年-2014间我院脑外科收治的54例脑胶质瘤患者。术前均常规行MRI、DWI和1H MRS检查。手术病理检查确诊脑胶质瘤。结果:正常脑白质、瘤周水肿、实性部分到囊变坏死部分的表观扩散系数(ADC)呈增高趋势,不同部位差异显著(P<0.01)。WHO 1-2级的ADC和相对表观扩散系数(r ADC)值分别为(153.66±15.92)×10^(-5)mm^2/s和(2.01±0.22)×10^(-5)mm^2/s,显著低于WHO 3-4级的(103.63±13.53)×10-5mm^2/s和(1.13±0.24)×10-5mm^2/s(P<0.01)。WHO 1-2级NAA/Cho、NAA/Cr和Cho/Cr分别为0.93±0.32、1.49±0.28和1.73±0.70,WHO 3-4级则分别为0.27±0.31、0.64±0.29和4.32±1.69,与正常组织相比差异显著(P<0.01)。结论:DWI和MRS对于脑胶质瘤的临床病理分级诊断有重要意义,有利于术前评估患者病情。
Objective：To analyze the diffusion weighted imaging（DWI） and pope analysis（MRS） in the clinical application of gloom.Methods：All 54 cases of gloom patients were selected.Preoperative routine MRI,DWI and ~1H MRS examination were performed.Results：The normal white matter,peritumoral edema,solid part to cystic necrosis ADC part were increased（P 0.01）.WHO 1-2 grade ADC and rADC values were（153.66±15.92）×10^（-5）mm^2/s and（2.01±0.22）×10^（-5）mm^2/s,significantly lower than WHO 3-4 grade（103.63±13.53）×10^（-5）mm^2/s and（1.13±0.24）×10^（-5）mm^2/s（P0.01）.WHO 1-2 NAA/Cho,NAA/Cr and Cho/Cr were 0.93±0.32,1.49 ±0.28 and 1.73±0.70,WHO 3-4 were 0.27±0.31,0.64±0.29 and 4.32±1.69,compared with the normal tissue P 0.01.Conclusion：DWI and MRS for brain gloom diagnosis is important.
出处
《现代肿瘤医学》
CAS
2016年第15期2374-2377,共4页
Journal of Modern Oncology
