摘要
卒中已成为中国居民的第一位死亡原因。作为缺血性卒中一级和二级预防的基石，阿司匹林在一定程度上能预防缺血性卒中的发病和复发。然而，部分患者在规律服用阿司匹林后仍然发生血管事件，或血小板聚集率较高，这种现象被称为“阿司匹林抵抗”或“阿司匹林低反应性”。文章对缺血性卒中患者阿司匹林抵抗的发生情况、检测方法和处理措施进行了综述。
Stroke has become the leading cause of death in Chinese residents. As the cornerstone of the primary and secondary prevention of ischemic stroke, aspirin can prevent the occurrence and recurrence of ischemic stroke in a certain extent. However, some patients stil have vascular events after taking aspirin regularly or higher platelet aggregation rate. This phenomenon is caled ＆quot;aspirin resistance＆quot; or ＆quot;aspirin low reactivity＆quot;. This article reviews the occurrence, detection methods, and treatment measures of aspirin resistance in patients with ischemic stroke.
出处
《国际脑血管病杂志》
2016年第5期442-446,共5页
International Journal of Cerebrovascular Diseases
关键词
卒中
脑缺血
阿司匹林
抗药性
Stroke
Brain Ischemia
Aspirin
Drug Resistance
