摘要
脑血管痉挛（CVS）是动脉瘤蛛网膜下腔出血（a SAH）常见的严重的并发症,CVS时因局部脑血管收缩使受累脑组织区域血供减少,从而引起缺血缺氧性神经功能损害而使患者致残、致亡、影响预后。尽管治疗a SAH的方法不断改进,但CVS仍然是a SAH致死或致残的主要原因。CVS经常发生在a SAH后的第3日,发病后第5~7日达到高峰,近年来随着科学研究的不断深入,已有很多药物用于预防或者治疗CVS。该文就近年来对于CVS的药物治疗种类、用药方式及疗效进行综述。
Cerebral vasospasm（CVS） is a common and serious complication of aneurysmal subarachnoid hemorrhage（aSAH）. CVS with the local cerebrovascular contraction reduce brain regions affects the blood supply,leading to ischemie hypoxic neural function damage and causing patients disability, death, and affecting the prognosis. Despite the continuous improvements in treatment of aSAH, CVS complicating aSAH has remained the main cause of morbidity and mortality. CVS begins most often on the third day after the aSAH event and reaches the maximum on the 5th-7th postictal days. With the deepening of the scientific research in recent years, several therapeutic modalities have been employed for preventing or reversing CVS. Here is to make a review of the available pharmacological treatment modalities for managing CVS.
出处
《医学综述》
2016年第13期2607-2612,共6页
Medical Recapitulate
关键词
脑血管痉挛
蛛网膜下腔出血
动脉瘤
药物治疗
Cerebral vasospasm
Subarachnoid hemorrhage
Aneurysms
Pharmacological treatment
