摘要
目的分析血浆前白蛋白水平对青年型脑梗死患者预后的影响。方法以2011年5月~2015年4月广东省惠州市第一人民医院神经内科收治120例青年型脑梗死患者为研究对象（观察组）,入院时和治疗后使用免疫透射比浊法检测患者的血浆前白蛋白水平,并选择同期体检的健康人员作为对照组。采集两组研究人员的血液指标,对比青年型脑梗死和健康人员、预后良好和预后不良患者的血浆前白蛋白水平,分析血浆前白蛋白与患者预后的关系,比较两组人员血浆前白蛋白水平,并分析前白蛋白水平与青年型脑梗死预后的关系。结果观察组患者的血浆前白蛋白水平为（243.5±23.6）mg/L,对照组为（281.6±26.3）mg/L,两组人员的血浆前白蛋白水平差异有统计学意义（P〈0.05）。预后良好103例,预后不良17例,预后良好患者的血浆前白蛋白水平为（263.9±25.5）mg/L,预后不良患者的血浆前白蛋白水平为（213.6±15.7）mg/L,预后良好和预后不良患者的血浆前白蛋白水平差异有统计学意义（P〈0.05）。血浆前白蛋白预测青年型脑梗死的灵敏度为85.83%,特异度为76.00%。结论血浆前白蛋白升高可能是青年型脑梗死发病的保护因素,血浆前白蛋白水平可作为青年型脑梗死预后质量的预测指标。
Objective To analyze the prognosis influence of prealbumin level in plasma on cerebral infarction in young adults.Methods From May 2011 to April 2015,120 young adult patients with cerebral infarction admitted into department of Neurology in Huizhou First People′ s Hospital in Guangdong were selected as research objects（observation group）.The prealbumin levels during hospitalization and after treatment were tested by immunity transmission turbidity.The healthy people for physical examinations at the same time were selected as control group.The blood indexes in both groups were collected in order to compare the prealbumin level in cerebral infarction in young adults and healthy participants,and between good prognosis and poor prognosis and analyze the relationship between prealbumin level in plasma and patient′s prognosis.The prealbumin levels in plasma in the two groups were compared.The relationship between prealbumin level and cerebral infarction in young adults were analyzed.Results In the observation group,the prealbumin level from plasma was（243.5±23.6） mg/L,while in the control group,the value was（281.6±26.3） mg/L with a statistical difference（P〈0.05）.The number of cases in good prognosis and poor prognosis was 103 and 17 respectively.The prealbumin level in good prognosis was（263.9±25.5） mg/L,while in poor prognosis was（213.6±15.7） mg/L,which was displayed a statistical difference（P〈0.05）.The sensitivity and specificity of cerebral infarction in young adults through prealbumin prognosis was 85.83% and 76.00% in turn.Conclusion Increasing of prealbumin may become a protective factor on the onset of cerebral infarction in young adults.The prealbumin level in plasma can be considered as a predictive index on the prognosis quality of cerebral infarction in young adults.
出处
《中国当代医药》
2016年第16期62-64,共3页
China Modern Medicine
关键词
血浆前白蛋白
青年型脑梗死
预后
Prealbumin in plasma
Cerebral infarction inyoung adults
Prognosis
