摘要
甲状腺功能障碍性视神经病变(DON)是甲状腺相关眼病(TAO)引起视神经功能损害的严重并发症,主要由眶内肿胀的眼外肌压迫眶尖视神经所致。早期诊治对疾病的疗效和预后至关重要。眼眶影像学检查在DON的诊断和评估上发挥着重要的作用,可以显示眼眶组织解剖结构,评估疾病分期及疗效,还能帮助识别倾向于发展为DON的患者。本文回顾了DON的病因、临床特征和影像学,着重对DON的影像学研究进行综述,包括CT、MRI和多普勒超声研究。
Dysthyroid optic neuropathy has long been recognized as the most feared complication of thyroid-associated ophthalmopathy,the most widely accepted mechanism is the compression of the optic nerve at the orbital apex by the enlarged extraocular muscles. Early diagnosis and timely treatment is essential for the curative effect and prognosis of the condition,and therefore avoiding permanent visual loss. Orbital imaging examination plays an important role both in the diagnosis and assessment of DON. Imaging studies can be used to evaluate morphological abnormalities of the orbital structures,to distinguish the inflammatory early stage from the inactive stage of the disease,and to monitor therapeutic response. Further,imaging studies can be of great help in identifying patients prone to develop dysthyroid optic neuropathy.This paper reviews the etiology,clinical features and imaging studies of DON,with special emphasis on the imaging studies,including computed tomography,magnetic resonance imaging,and Doppler ultrasound.
出处
《临床眼科杂志》
2016年第3期269-273,共5页
Journal of Clinical Ophthalmology
基金
国家高技术研究发展计划(863计划)(2015AA020311)
