摘要
目的:探讨尿激酶预防性封管对保持血液透析用半永久性导管通畅的效果及安全性。方法:使用半永久性导管的维持性透析患者40例随机分成两组,研究组定期尿激酶与肝素混合液封管,对照组常规肝素封管。同时观察这两组病人1年内血透平均流速、更换导管率等并监测患者的凝血功能。结果:研究组透析时平均血流速度明显优于对照组,每月抽吸不畅例次、住院溶栓治疗例次及更换导管率明显少于对照组,差异具有统计学意义,患者凝血功能无明显影响。结论:定期使用尿激酶及肝素混合液预防性封管的方法可维持半永久性导管的通畅性,且不增加出血风险。
Objective： To investigate the efficacy and safety of urokinase sealing tube in the prevention of semi permanent catheter patency in hemodialysis patients. Methods： 40 patients were randomly divided into two groups using semi permanent catheter maintenance dialysis patients. The study group is with regular urokinase and heparin mixture sealing tube,and the control group is with conventional heparin sealing tube. At the same time,observation of the two groups of patients in one year,the average blood flow velocity,the replacement of catheter rate and the patient＇s blood coagulation function were monitored. Results： The average blood flow rate in the study group was significantly better than that in the control group,The monthly poor cases,suction treatment cases and catheter replacement rate of thrombolysis was significantly less than the control group,the difference was statistically significant. There was no significant effect of coagulation function in patients. Conclusion： The use of urokinase and heparin to prevent the closure of the method can be used to maintain the patency of semi permanent catheter,and does not increase the risk of bleeding.
出处
《宜春学院学报》
2016年第6期62-64,共3页
Journal of Yichun University
