期刊文献+

带状疱疹后遗神经痛的治疗进展 被引量:25

Treatment of postherpetic neuralgia
原文传递
导出
摘要 目前针对带状疱疹后遗神经痛的治疗,虽无特效方法,但通过恰当的综合治疗可最大程度缓解患者的症状。抗惊厥药如加巴喷丁和普瑞巴林、三环类抗抑郁药仍是常用药物。外用治疗为临床推荐的方法之一,其中辣椒素高浓度贴剂可用于其他治疗无效或无法耐受系统治疗者。而麻醉镇痛药、神经阻滞疗法等因其不良反应较大,不作为一线疗法。此外,新兴药物肿瘤坏死因子α抑制剂、自控镇痛技术等方法在带状疱疹后遗神经痛患者中的应用逐渐受到重视。 At present, there is no special therapy for postherpetic neuralgia (PHN), but the symptoms of PHN can be alleviated to the maximum extent by appropriate comprehensive therapy. Anticonvulsants are still commonly used drugs, including gabapentin, pregabalin and tricyclic antidepressants. Topical treatment is a recommended therapeutic approach to PHN in clinic. High-concentration capsaicin patches can be applied in patients who fail to respond to other treatments or cannot tolerate systemic therapies. Neither narcotic analgesics nor nerve block therapy is recommended as the first-line therapy because of their adverse effects. In addition, the application of new drugs such as tumor necrosis factor?-α inhibitors and patient?-controlled analgesia in patients with PHN have gained increasing attention.
出处 《国际皮肤性病学杂志》 2016年第4期209-211,共3页 International Journal of Dermatology and Venereology
关键词 神经痛 带状疱疹后 治疗应用 药用制剂 外用药 物理治疗技术 心理治疗过程 Neuralgia, postherpetic Therapeutic uses Pharmaceutical preparations External application drugs Physical therapy modalities Psychotherapeutic processes
  • 相关文献

参考文献22

  • 1Hiom S, Patel GK, Newcombe RG, et al. Severe postherpetic neuralgia and other neuropathic pain syndromes alleviated by topical gabapentin [J3. Br J Dermatol, 2015, 173 (1): 300-302. DOI: 10.1111/bjd.13624. 被引量:1
  • 2Takao Y, Miyazaki Y, Okeda M, et al. Incidences of herpes zoster and postherpetic neuralgia in Japanese adults aged 50 years and older from a community-based prospective cohort study: the SHEZ study[J]. J Epidemiol, 2015, 25(10): 617-625. DOI: 10.2188/jea.JE20140210. 被引量:1
  • 3Bayat A, Burbelo PD, Browne SK, et al. Anti-cytokine autoantibodies in postherpetic neuralgia[J]. J Transl Med, 2015, 13: 333. DOI: 10.1186/s12967-015-0695-6. 被引量:1
  • 4Sang CN, Sathyanarayana R, Sweeney M. Gastroretentive gabapentin (G-GR) formulation reduces intensity of pain associated with postherpetic neuralgia (PHN) [J]. Clin J Pain, 2013, 29(4): 281-288. DOI: lO.1097/AJP.ObO13e318258993e. 被引量:1
  • 5Irving GA, Sweeney M. Tolerability and safety of gastroretentive once-daily gabapentin tablets for the treatment of postherpetic neuralgia [J~. J Pain Res, 2012, 5: 203-208. DOI: 10.2147/JPR. $32562. blarkley. 被引量:1
  • 6HG, Dnnteman ED, Kareht S, et al. Real-world experience with once-daily gabapentin for the treatment of postherpetic neuralgia (PHN)[J~. Clin J Pain, 2015, 31 (1): 58- 65. DOI: 10.1097/AJP.0000000000000082. 被引量:1
  • 7Moore RA, Derry S, Ald ington D, et al. Amitriptyline for neumpathic pain in adults ~J]. Cochrane Database Syst Rev,.2015, 7: CD008242. DOI: 10.1002/14651858.CD008242. 被引量:1
  • 8Teixeira M J, Okada M, Moseoso AS, et al. Methadone in post- herpetic neuralgia: a pilot proof-of-concept study [J]. Clinics (Sao Paulo), 2013, 68 (7): 1057-1060. DOI: 10.6061/clinics/ 2013(07)25. 被引量:1
  • 9Seheneking M, Vollbracht C, Weiss G, et al. Intravenous vitamin C in the treatment of shingles: results of a multicenter prospective cohort study [J]. Med Sci Monit, 2012, 18 (4): CR215-224. 被引量:1
  • 10Sharma M, Garigipati S, Kundu B, et al. Discovery of novel 1,2,4-triazol-5-ones as tumor necrosis factor-alpha inhibitors for the treatment of neumpathic pain [J]. Chem Biol Drug Des, 2012, 80(6): 961-970. DOI: 10.1111/cbdd.12049. 被引量:1

同被引文献193

引证文献25

二级引证文献164

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部