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睡眠质量与维持性血液透析患者心包脏层脂肪体积相关性研究 被引量:1

Correlation study of sleep quality and volume of epicardial adipose tissue in patients with maintenance hemodialysis
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摘要 目的探讨血液透析患者睡眠障碍与心包脏层脂肪组织(EAT)体积的潜在关系。方法选择透析时间超过3个月且病情比较稳定的维持性血液透析(MHD)患者82例,根据匹兹堡睡眠质量量表(PSQI)积分分为两组,睡眠障碍组(PQSI>5分)和对照组(PQSI≤5分)。观察两组PQSI、爱泼沃思嗜睡量表(ESS)、心包脏层脂肪的体积,并探讨血液透析患者睡眠质量与心包脏层脂肪的体积的相关性。结果两组患者性别和年龄均差异无统计学意义(P>0.05),但睡眠障碍组患者CRP,瘦素较对照组更高,差异有统计学意义。睡眠障碍组EAT体积(170.0±17.0)cm3,对照组EAT体积(141.9±22.4)cm3,两组EAT差异有统计学意义(P<0.05)。结论维持性血液透析患者发生睡眠质量与EAT体积的改变存在相关关系。 Objective To explore the potential relationship between sleep disorders and volume of epicardial adipose tissue (EAT).Methods Eighty-two cases of MHD patients with dialysis more than 3 months were chosen in our hemodialysis center from January 2013 to August 2014 and were divided into two groups(PSQI≤5 and PSQI 〉5) according to PSQI score.PSQI,ESS,volume of epicardial fat tissuewere observe,and explore the relationship of sleep quality and epicardial fat volume.Results There were nosignificant differences in the age,gender between two groups (P 〉0.05).The CRP and leptin in sleep disorder group was higher than that in the control group(P 〈0.05).EAT volume of sleep disorder group and control group were(170.0 ±17.0)cm3 and (141.9 ±22.4)cm3 ,respectively,which had statistical difference(P 〈0.05).Conclusions EAT volume change and sleep disorder exist a certain relationship in patients with maintenance hemodialysis.
出处 《中国临床保健杂志》 CAS 2016年第4期377-380,共4页 Chinese Journal of Clinical Healthcare
基金 温州市2014年第二期科技计划项目(Y20140286)
关键词 肾透析 睡眠障碍 脂肪组织 Renal dialysis Sleep disorders Adipose tissue
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