摘要
目的探讨降钙素原(PCT)、超敏C反应蛋白(hs-CRP)、白细胞计数(WBC)、中性粒细胞(NEUT)等炎性指标在一些感染性和非感染性疾病中的表达及与血培养的相关性。方法 244例患者中感染组184例,其中肺部感染亚组105例和其他感染亚组79例,非感染组60例。检测患者的PCT、hs-CRP、WBC及NEUT,然后将检测结果在各组进行对比。结果肺部感染亚组和其他感染亚组PCT水平和阳性率明显高于非感染组(P<0.05),而肺部感染亚组又明显高于其他感染亚组(P<0.05)。肺部感染亚组和其他感染亚组hs-CRP阳性率均大于90%,WBC及NEUT水平和阳性率明显高于非感染组(P<0.05)。血培养阳性率在肺部感染亚组为49.5%,与hs-CRP、WBC和NEUT有较好的相关性(P<0.05);其他感染亚组为51.9%,与WBC和NEUT有很好的相关性(P<0.05);在非感染组为16.7%,与PCT、WBC和NEUT有较好的相关性(P<0.05)。结论 PCT、hsCRP及WBC检测可作为多种疾病的辅助诊断指标,可为这些疾病的早期治疗及合理使用抗菌药物提供依据。
Objective To explore the expression of four inflammatory makers in infectious diseases and noninfectious diseases and relevance with blood culture.Methods A total of 244 cases of patients were selected as objects in this study,and 184 patients in infectious diseases group,60 patients in noninfectious diseases group.184 patients in infectious diseases group were divided into pulmonary infection group（105patients）and other infection group（79patients）.Procalcitonin（PCT）,high-sensitivity C-reactive protein（hs-CRP）,white blood cell（WBC）,and neutrophil（NEUT）were tested in the patients and the tested results were compared.Results The PCT levels and positive rates in pulmonary infection group and other infection group were significant higher than noninfectious diseases group（P〈0.05）,however the pulmonary infectious group were significant higher than other infectious diseases group（P〈0.05）.The hs-CRP positive rates in pulmonary infection group and other infection group were greater than90.0%,the WBC and NEUT level and positive rates in pulmonary infection group and other infection group were significant higher than noninfectious group（P〈0.05）.The blood-culture positive rate was 49.5%in the pulmonary infectious group,and had better relevance with the hs-CRP,WBC and NEUT（P〈0.05）.The blood-culture positive rate was 51.9%in the other infectious diseases group,and had good relevance with the WBC and NEUT（P〈0.05）The blood-culture positive rate was 16.7%in the noninfectious group,and had better relevance with the PCT,WBC and NEUT（P〈0.05）.Conclusion The determinations of PCT,hs-CRP and WBC might act as the assistant diagnostic indicators for various diseases,and might provide the basis in terms of the treatments of early stage and the rational use of antibiotics for these diseases.
出处
《国际检验医学杂志》
CAS
2016年第12期1615-1618,共4页
International Journal of Laboratory Medicine
基金
广东省江门市卫计局立项课题项目(15A127)
关键词
降钙素原
血培养
感染性疾病
非感染性疾病
procalcitonin
blood-culture
infectious disease
noninfectious disease
