摘要
滇龙胆Gentiana rigescens为传统中草药,主产于中国云南、四川等地,具有悠久的药用历史,作为民间重要药物使用并记载。滇龙胆为龙胆科Gentianaceae多年生草本植物,主要化学成分为环烯醚萜苷类、三萜类、木脂素类、黄酮类、生物碱类、苯甲酸酯类和其他类化学成分,其主要药理作用包括保肝、利胆、镇痛、抗炎、抗氧化、促神经活化等。该文对滇龙胆中化学成分及其药理活性进行归纳总结,为滇龙胆的进一步开发和利用提供参考。
Objective: Gentiana rigescens,mainly distributed in Yunnan and Sichuan province of China,is widely known as traditional Chinese herbs in folk with long medicinal history. G. rigescens( Gentianaceae),is a kind of perennial herb,whose chemical constituents mainly include iridoids,triterpenes,lignans,flavanoids,alkaloids,gentisides and others. Their main pharmacological effects include liver protection,choleretic effect,analgesia,anti-inflammatory,anti-oxidant,promoting neural activation and so on. This paper would summarize the chemical constituents and pharmacological activity of G. rigescens,and provide reference for further development and utilization of G. rigescens.
出处
《中国实验方剂学杂志》
CAS
CSCD
北大核心
2016年第13期213-222,共10页
Chinese Journal of Experimental Traditional Medical Formulae
基金
国家自然科学基金项目(81260608)
云南省自然科学基金项目(2013FZ150)
云南省自然科学基金项目(2013FZ151)
关键词
滇龙胆
化学成分
药理活性
研究进展
Gentiana rigescens
chemical constituent
pharmacological activity
research advances