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化疗联合细胞免疫治疗用于复发性卵巢癌的疗效观察 被引量:2

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摘要 目的:观察分析化疗联合细胞免疫治疗用于复发性卵巢癌的临床效果。方法:选取我院收治的99例复发性卵巢癌患者,采用随机数字表法分为观察组和对照组。对照组49例患者行化疗治疗,观察组50例患者行化疗联合细胞免疫治疗。分析比较两组患者的无进展生存期(PFS)、总生存期(OS)、不良反应发生率和治疗前后两组患者的总T细胞(CD3^+)、NK细胞(CD3-CD56^+)和CD19^+B细胞(CD19^+)水平变化。结果:治疗前,两组患者的CD3^+、CD3-CD56^+和CD19^+水平比较无统计学意义(P>0.05);治疗后,两组患者的CD3^+水平无明显变化,差异无统计学意义(P>0.05);CD3-CD56^+和CD19^+水平显著上升,观察组患者的CD3-CD56^+和CD19^+水平高于对照组,观察组PFS和OS长于对照组,差异有统计学意义(P<0.05);两组患者的不良反应发生率比较差异无统计学意义(P>0.05)。结论:化疗联合细胞免疫治疗用于复发性卵巢癌,能显著提高患者部分细胞免疫力,并延长患者的生存期,值得推广使用。
出处 《中外女性健康研究》 2016年第9期218-218,221,共2页 Women's Health Research
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