期刊文献+

BCR-ABL融合基因在慢性粒细胞白血病临床诊治中的研究进展 被引量:9

下载PDF
导出
摘要 BCR-ABL融合基因是慢性粒细胞白血病(CML)的特征性标志,根据BCR的断裂位置主要分为3个类型:M-BCR、m-BCR及μ-BCR。采用分子生物学技术检测BCR-ABL融合基因的表达、突变对于CML的临床诊断、治疗以及预后都具有非常重要的意义。
出处 《中南医学科学杂志》 CAS 2016年第3期356-360,共5页 Medical Science Journal of Central South China
基金 深圳市盐田区科技计划资助项目(201301)
  • 相关文献

参考文献39

  • 1Goldman JM,Melo JV.Chronic myeloid leukemia——advances in biology and new approaches to treatmen[J].N Engl J Med,2003,349(15):1451-1464. 被引量:1
  • 2Jabbour E,Kantarjian H.Chronic myeloid leukemia:2014update on diagnosis,monitoring,and management[J].Am J Hematol,2014,89(5):547-556. 被引量:1
  • 3Nowell PC,Hungerford DA.Chromosome studies on normal and leukemic human leukocytes[J].J Natl Cancer Inst,1960,25:85-109. 被引量:1
  • 4Nowell PC,Hungerford DA.Chromosome studies in human leukemia.II.Chronic granulocytic leukemia[J].J Natl Cancer Inst,1961,27:1013-1035. 被引量:1
  • 5Rowley JD.Letter:A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining[J].Nature,1973,243(5405):290-293. 被引量:1
  • 6Groffen J,Stephenson JR,Heisterkamp N,et al.Philadelphia chromosomal breakpoints are clustered within a limited region,bcr,on chromosome 22[J].Cell,1984,36(1):93-99. 被引量:1
  • 7Daley GQ,Van Etten RA,Baltimore D.Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome[J].Science,1990,247(4944):824-830. 被引量:1
  • 8Erba HP.Molecular monitoring to improve outcomes in patients with chronic myeloid leukemia in chronic phase:importance of achieving treatment-free remission[J].Am J Hematol,2015,90(3):242-249. 被引量:1
  • 9O'Brien SG,Guilhot F,Larson RA,et al.Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia[J].N Engl J Med,2003.348(11):994-1004. 被引量:1
  • 10Faderl S,Hochhaus A,Hughes T.Monitoring of minimal residual disease in chronic myeloid leukemia[J].Hematol Oncol Clin North Am,2004,18(3):657-670. 被引量:1

同被引文献79

引证文献9

二级引证文献47

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部