摘要
目的:在体动态观察微创埋线后线体对正常人体经穴局部刺激效应的时效特点,为微创埋线疗法间隔周期提供参考依据。方法:应用医学影像学MRI扫描技术采集8例健康受试者左侧三阴交穴埋线前后多个时间点局部T2WI压脂像及T2Mapping 8回波序列MRI图像,8回波系列图像再利用FuncTool软件生成T2 Mapping图像后,测量埋线局部T2均值,分析三阴交穴微创埋线后局部T2WI压脂像信号强度及T2均值随时间变化的特点。结果:与埋线前相比,埋线后8h局部T2WI压脂像信号强度及T2均值开始升高(P<0.01),埋线后第3、7d局部T2WI压脂像信号强度及T2均值明显升高(均P<0.01);埋线后第14d局部T2WI压脂像信号及T2均值较前两个时间点下降,但仍高于埋线前(均P<0.01);埋线后第21、28、35d,埋线局部T2压脂像信号强度及T2均值下降至接近埋线前(均P>0.05)。结论:三阴交穴施行微创埋线后,线体对三阴交穴的刺激效应周期约为21d。相同条件下施行微创埋线时,选用与三阴交穴组织结构相近的穴位,其埋线间隔周期的选择可以21d为参考。
Objective To in vivo dynamically observe the time-effect characteristic of local stimulating effect on acupoints after micro-invasion embedding,which could provide references for the interval period of micro-invasion embedding.Methods With magnetic resonance imaging（MRI）technique,the local T2 WI fat-suppression images and T2 Mapping 8-echo sequence images were collected at multiple time points from 8 healthy subjects who received embedding at left Sanyinjiao（SP 6）.After the 8-echo sequence images were transformed into T2 Mapping images by using software FuncTool,the T2 average value of embedding area was measured,and the changes of local signal strength of T2 WI fat-suppression images and T2 average value along with time after embedding at left Sanyinjiao（SP 6）were analyzed.Results Compared before embedding,the signal strength of local T2 WI fatsuppression images and the T2 average value began to increase 8hafter being embedded（P〈0.01）;the signal strength of T2 WI fat-suppression images and the T2 average value were significantly increased 3dand 7dafter being embedded（all P〈0.01）;the signal strength of local T2 WI fat-suppression images and the T2 average value14dafter being embedded were lower than those at previous 2time points,but higher than those before embedding（both P〈0.01）;21d,28 dand 35dafter embedding,the signal strength of local T2 WI fat-suppression images and the T2 average value were similar to those before treatment（all P〈0.05）.Conclusion After micro-invasion embedding at Sanyinjiao（SP 6）,the stimulation effect period on acupoint is approximately 21 days.When applying micro-invasion embedding under similar condition at acupoints which has similar structure as Sanyinjiao（SP 6）,the interval period of embedding could consider 21 days as a reference.
出处
《中国针灸》
CAS
CSCD
北大核心
2016年第6期607-611,共5页
Chinese Acupuncture & Moxibustion
基金
贵州省中医药管理局项目:QZYY2013-86
关键词
微创埋线
刺激效应
磁共振成像T2图
疗程
micro-invasion embedding
stimulating effect
magnetic resonance imaging T2Mapping
course of treatment
