摘要
目的分析沐舒坦不同给药途径在治疗新生儿肺炎中的临床疗效。方法 2012年8月至2014年10月河南省汝阳县人民医院儿科收治住院的新生儿肺炎患者86例,依据治疗方案的不同将其分为对照组和观察组各43例。对照组给予恒温箱保暖、吸氧、抗感染治疗、纠正酸碱失衡、能量合剂营养支持等常规对症治疗,同时静脉滴注沐舒坦治疗;观察组在上述治疗基础上,给予沐舒坦雾化吸入治疗。观察比较两组患儿治疗时间、临床疗效以及药物不良反应发生情况。结果观察组总有效率比较差异无统计学意义(P>0.05),观察组痊愈率为95.4%(41/43),显著高于对照组79.1%(34/43),差异有统计学意义(P<0.05)。观察组治疗时间为(7.4±2.1)d,显著低于对照组(10.4±2.9)d,差异有统计学意义(P<0.05)。治疗期间两组患儿药物不良反应轻微,差异无统计学意义(P>0.05)。结论沐舒坦雾化吸入配合静脉滴注使用可快速控制患儿临床症状,缩短治疗时间,提高治愈率,且患儿无明显不良反应,安全性较好。
Objective To investigate the clinical effect of mucosolvan given in different ways in the treatment of neonatal pneumonia. Methods Totally 86 cases of neonatal pneumonia were selected in the Pediatric Department of People＇s Hospital of Ruyang County from Aug. 2012 to Oct. 2014,and according to the different treatment options they were divided into control group and observation group, 43 cases in each group. The control group was given constant temperature incubator, oxygen, anti-infection, correction of acidbase imbalance,energy mixture of nutritional support and other conventional symptomatic treatment. At the same time,intravenous infusion of mucosolvan treatment was given. The observation group was given muco- solvan inhalation therapy in addition to the above treatment. The treatment time, clinical efficacy and adverse drug reactions were observed and compared between the two groups. Results There was no significant difference in the total effective rate between the two groups（P〉0. 05）. The cure rate of observation group was 95.4% （41/43）, significantly higher than that of the control group[79.1% （34/43）], the difference being statistically significant （P〈0.05）. In the observation group, treatment time was （ 7.4 ±2.1 ） d, significantly shorter than the control group （ 10.4± 2.9） d, the difference being statistically significant （P 〈 0.05 ）. Adverse drug reactions were mild in the two groups during the treatment period, the difference being not statistically significant（P〉0.05）. Conclusion Mucosolvan aerosol inhalation combined with intravenous use can control clinical symptoms quickly, shorten the treatment time and improve the cure rate. It is safer and has no obvious adverse drug reactions.
出处
《中国中西医结合儿科学》
2016年第3期335-337,共3页
Chinese Pediatrics of Integrated Traditional and Western Medicine
关键词
肺炎
沐舒坦
静脉滴注
雾化吸入
婴儿
新生
Pneumonia
Mucosolvan
Intravenous infusion
Atomizing inhalation
Infant, newborn
