摘要
多凝集红细胞抗原是一组不符合免疫学规律,没有特定的抗体反应、呈多凝集现象的一组红细胞。根据Bird的定义：＂与血型无关,与所有血清抗体都反应＂。最早是在1930年Thomsen和Friendrich发现这一现象。多凝集红细胞是因为各种原因而产生的膜抗原暴露,从而产生的＂多凝集＂现象,这与临床疾病相关、与人体免疫机制相关,与红细胞免疫相关。
The multi-agglutination red cell antigens are a group of non-specific antibody reaction antigen,mostly related to clinical disease.Because of antigen membrane exposure and antigenicity,these red blood cells produce multi agglutination phenomenon,which could be detected by phytohemagglutinin as identification reagent.The researches of the genetics and molecular biology of T antigen showed that it was expected to become an independent blood group antigen.This paper introduces the multi-agglutination antigen associated with disease.
出处
《临床血液学杂志（输血与检验）》
CAS
2016年第3期512-517,共6页
Journal of Clinical Hematology(Blood Transfusion & Laboratory Medicine)
关键词
多凝集红细胞
红细胞免疫机制
植物血凝素
T/Tn多凝集抗原与基因
multi agglutination of red blood cells
red blood cell immune mechanism
PHA
T poly agglutination antigen and gene
