摘要
目的:分析胰十二指肠切除术后胃瘫综合征发生的危险因素。方法:回顾性分析497例胰十二指肠切除术患者的临床资料,以手术后是否发生胃瘫综合征为因变量,对临床资料进行统计学检验,有统计意义的变量再引入二分类非条件逐步Logistic回归模型进行多因素分析,确定独立的危险因素。结果:单因素分析结果显示,ASA评分(P=0.039)、年龄(P=0.014)、术后应用生长抑素(P=0.003)、胰管支撑管长度(P=0.027)、胰管直径(P=0.007)均是胰十二指肠切除术术后胃瘫发生的危险因素;多因素非条件Logistic回归分析结果显示,年龄(P=0.001)、术后应用生长抑素(P=0.026)是胰十二指肠切除术术后胃瘫综合征发生的独立危险因素。结论:患者年龄较大、术后应用生长抑素易发生胰十二指肠切除术术后胃瘫综合征,提高手术精细度、适当增加胰管支撑管的长度,可能减少胰十二指肠切除术术后胃瘫综合征的发生率。
Objective To investigate the risk factors of postoperative gastroparesis syndrome in patients undergoing pancreaticoduodenectomy.Methods A retrospective review was performed on the medical records of 497 patients undergoing pancreaticoduodenectomy. With or without gastroparesis syndrome after operation as thedependent variable, all cases were carried out on the clinical data of statistical tests, and those with statistically significant variables were studied to introduce two classifications on unconditioned stepwise Logistic regressionmodel for multiple factors analysis, to identify independent risk factors.Results Single factor analysis resultsshowed that ASA score, age, postoperative application of somatostatin, pancreatic duct supporting tube length,and the diameter of the pancreatic duct, all were the risk factors for pancreaticoduodenectomy postsurgical gastroparesis syndrome. Multi-factor unconditioned Logistic regression analysis results showed that age, and postopera-tive application of somatostatin were the independent risk factors for pancreaticoduodenectomy postsurgical gastroparesis syndrome.Conclusion Postoperative somatostatin makes older patients more prone to gastroparesissyndrome after pancreaticoduodenectomy. To improve the operation precision, increasing the length of the pancreatic duct supporting tube, the incidence of postsurgical gastroparesis syndrome after pancreaticoduodenectomymay be reduced.
出处
《中国中西医结合外科杂志》
CAS
2016年第3期224-227,共4页
Chinese Journal of Surgery of Integrated Traditional and Western Medicine
关键词
胰十二指肠切除术
胃瘫综合征
危险因素
Pancreaticoduodenectomy
postsurgical gastroparesis syndrome
risk factors
