摘要
目的观察十二指肠镜联合腹腔镜治疗急性胆源性胰腺炎的疗效和安全性。方法选取接受治疗的急性胆源性胰腺炎患者84例，采用随机数字表法分为两组，研究组和对照组各42例。对照组给予内科保守方法治疗，研究组采用十二指肠镜联合腹腔镜治疗。观察并比较两组疗效和不良反应发生情况。结果研究组体温恢复正常时间、腹痛缓解时间、尿淀粉酶恢复正常时间、生化指标恢复正常时间、住院时间分别为（3．44±1．63）d、（4．73±1．12）d、（7．82±3．31）d、（9．81±6．42）d、（12．43±4．61）d，对照组分别为（5．94±2．43）d、（7．53±2．12）d、（11．72±2．21）d、（18．41±8．62）d、（20．33±6．21）d，两组差异均有统计学意义（t ＝3．90、4．02、4．26、4．50、5．01，均 P ＜0．05）。研究组治疗后发生胆道出血2例、胰腺假性囊肿2例、切口感染1例，无复发患者，不良反应发生率为11．90％；对照组经治疗后发生胰腺假性囊肿3例、腹腔脓肿2例、复发5例、急性呼吸窘迫综合征（ARDS）1例、肾功能衰竭1例，不良反应发生率为28．57％，研究组不良反应发生率低于对照组（χ^2＝4．21，P ＜0．05）。结论十二指肠镜联合腹腔镜治疗急性胆源性胰腺炎效果好、住院时间短、花费少、不良反应少，复发率低。
Objective To observe the efficacy and safety of endoscope and laparoscope in treatment of acutebiliary pancreatitis.Methods 84 patients with acute biliary pancreatitis from January 2010 to January 2014 in our hospital during treatment were randomly divided into the study group and control group according to the random num-ber table methods,42 cases in each group.The control group was treated with conservative treatment of department of internal medicine,while the study group was treated with duodenoscopy combined with laparoscopy.To observe and compare the efficacy and adverse reactions of two groups.Results Temperature returned to normal time,abdominal pain relief time,recovery time of amylase in urine,recovery time of biochemical index,hospitalization time and cost of hospitalization of the study group after treatment were （3.44 ±1.63）d,（4.73 ±1.12）d,（7.82 ±3.31）d,（9.81 ± 6.42）d,（12.43 ±4.61 ）d,which were significantly lower than （5.94 ±2.43）d,（7.53 ±2.12）d,（11.72 ± 2.21）d,（18.41 ±8.62）d,（20.33 ±6.21）d of the control group（t =3.90,4.02,4.26,4.50,5.01,all P 〈0.05）. 2 cases of the study group occured biliary tract bleeding,2 cases with pancreatic pseudocyst,1 case with wound infec-tion,there was no recurrence,the incidence rate of adverse reaction was 11.90%;3 cases of the control group after treatment occurred pancreatic pseudocyst,2 cases with abdominal cysts,5 cases with recurrence,1 case with acute respiratory distress syndrome （ARDS）,1 case with renal failure,the incidence rate of adverse reactions was 28.57%, which of the control group was significantly higher than the study group （χ^2 =4.21,P 〈0.05 ）.Conclusion Duodenal endoscopy combined with laparoscopy has good clinical effect,shorter hospitalization time,less cost,less adverse reaction and the recurrence rate is low in treatment of acute biliary pancreatitis,which has high application value.
出处
《中国基层医药》
CAS
2016年第12期1857-1860,共4页
Chinese Journal of Primary Medicine and Pharmacy
