摘要
目的探讨体外反搏技术对慢性充血性心力衰竭患者左心室收缩功能的影响及临床效果。方法选择300例慢性充血性心力衰竭患者作为研究对象，以数字表法随机分为观察组和对照组，对照组150例患者给予常规药物进行治疗，观察组150例患者在对照组的基础上给予体外反搏技术进行治疗。观察两组患者治疗前后的脑钠肽（BNP）、6min步行距离、左心室收缩功能等情况；比较两组患者的不良反应及临床疗效。结果治疗后，观察组6min步行距离[（471．2±35．8）m]、左心室收缩功能[（48．6±7．6）％]均优于对照组的（431．6±33．7）m、（42．7±5．2）％（t=0．875，P〈0．05；t=1．367，P〈0．05）；观察组BNP[（438．9±386．5）fmol／mL]明显低于对照组的（675．2±438．7）fmol／mL（t=1．256，P〈0．05）；两组不良反应差异无统计学意义（P〉0．05）。结论通过采用体外反搏技术治疗慢性充血性心力衰竭患者的临床疗效显着，能够改善患者的左心室收缩功能，值得临床长期推广应用。
Objective To explore the effect of external eounterpulsation on the left ventricular systolic function in patients with chronic congestive heart failure. Methods 300 patients with chronic congestive heart failure were selected as the research subjects,they were randomly divided equally into observation group and control group. 150 cases in the control group were given routine drug treatment, 150 cases in the observation group were treated with extracorporeal counterpulsation treatment on the basis of the control group. The brain natriuretic peptide （ BNP）, 6 min walking distance and left ventricular systolic function were observed before and after treatment in the two groups. The adverse reactions and clinical efficacy of the two groups were compared. Results After treatment, 6 minutes walking distance, left ventricular systolic function of the observation group were （4. 712 ± 35. 8 ） m, （48.6 ± 7.6 ） %, which were significantly better than those of the control group [ （ 43. 16 ± 3.37 ） m, （ 42.7 ± 5.2% ）, t = 0. 875,1. 367, all P 〈 0. 05 ]. The BNP level of the observation group （438.9 ± 386.5 ） fmol/mL was significantly lower than （675.2 ±438.7） fmol/mL of the control group（t = 1. 256,P 〈0.05）. The adverse reactions of the two groups had no significant difference （P 〉 0. 05 ）. Conclusion External counterpulsation technology in the treatment of patients with chronic congestive heart failure has significant clinical effect, can improve the left ventricular systolic function in patients, it is worthy of clinical application.
出处
《中国基层医药》
CAS
2016年第12期1807-1810,共4页
Chinese Journal of Primary Medicine and Pharmacy
基金
广东省中山市科学技术局项目（2014A1FC087）
关键词
反搏技术
心力衰竭
心脏功能试验
Counterpulsation
Heart failure
Heart function tests
